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Abstract：
OBJECTIVE: Besides correcting malocclusions, another main objective of orthodontic treatment is to improve patients\' oral health-related quality of life (OHRQoL). This study aimed to assess changes in OHRQoL of children within the first six months of orthodontic therapy with fixed orthodontic appliances.
METHODS: 85 patients aged 11 to 14 years requiring fixed orthodontic appliance therapy were included. The children completed the German version of the Child Perceptions Questionnaire (CPQ-G-11-14) before (T0), 1 month (T1) and 6 months (T2) after the start of orthodontic treatment. The type of malocclusion was categorized according to the Index of Orthodontic Treatment Need (IOTN).
RESULTS: The initial type of malocclusion affected the children\'s OHRQoL, whereas gender and age did not. The IOTN dental health component (DHC) had a significant impact on the CPQ score (median CPQ of 15.00 for the group DHC 4 vs. 22.50 for DHC 5, p = 0.032). The onset of orthodontic treatment initially affected the CPQ domains \"Oral symptoms\" and \"Functional limitations, with a change versus baseline of 2.00 (p = 0.001), but improved again after 6 months. Regression analysis demonstrated that children with an IOTN DHC 5 malocclusion experienced a greater impact on their ORHQoL, as indicated by a CPQ score 7.35 points higher than that of children with an IOTN DHC 4 malocclusion (p = 0.015).
CONCLUSIONS: At the beginning of orthodontic treatment, the OHRQoL slightly worsens, probably due to the discomfort and appearance of the appliances. However, 6 months after the start of orthodontic treatment, OHRQoL improved again in patients with severe malocclusion (IOTN 4 and 5), and approached baseline values.
CONCLUSIONS: The results help the clinician to better understand specific aspects of oral health that may be affected by different malocclusions, thereby improving the child\'s satisfaction and overall quality of life.
METHODS: 85 patients aged 11 to 14 years requiring fixed orthodontic appliance therapy were included. The children completed the German version of the Child Perceptions Questionnaire (CPQ-G-11-14) before (T0), 1 month (T1) and 6 months (T2) after the start of orthodontic treatment. The type of malocclusion was categorized according to the Index of Orthodontic Treatment Need (IOTN).
RESULTS: The initial type of malocclusion affected the children\'s OHRQoL, whereas gender and age did not. The IOTN dental health component (DHC) had a significant impact on the CPQ score (median CPQ of 15.00 for the group DHC 4 vs. 22.50 for DHC 5, p = 0.032). The onset of orthodontic treatment initially affected the CPQ domains \"Oral symptoms\" and \"Functional limitations, with a change versus baseline of 2.00 (p = 0.001), but improved again after 6 months. Regression analysis demonstrated that children with an IOTN DHC 5 malocclusion experienced a greater impact on their ORHQoL, as indicated by a CPQ score 7.35 points higher than that of children with an IOTN DHC 4 malocclusion (p = 0.015).
CONCLUSIONS: At the beginning of orthodontic treatment, the OHRQoL slightly worsens, probably due to the discomfort and appearance of the appliances. However, 6 months after the start of orthodontic treatment, OHRQoL improved again in patients with severe malocclusion (IOTN 4 and 5), and approached baseline values.
CONCLUSIONS: The results help the clinician to better understand specific aspects of oral health that may be affected by different malocclusions, thereby improving the child\'s satisfaction and overall quality of life.
摘要：
目的：除了纠正错牙合，正畸治疗的另一个主要目标是改善患者口腔健康相关生活质量(OHRQoL)。这项研究旨在评估使用固定正畸矫治器进行正畸治疗的前六个月内儿童OHRQoL的变化。
方法：纳入85例11~14岁需要固定正畸矫治器治疗的患者。孩子们在（T0）之前完成了德语版的儿童感知问卷（CPQ-G-11-14），1个月（T1）和6个月（T2）后开端正畸医治。根据正畸治疗需求指数（IOTN）对错牙合的类型进行分类。
结果：最初类型的错牙合影响了儿童的OHRQoL，而性别和年龄没有。IOTN牙齿健康成分（DHC）对CPQ评分有显著影响（DHC4组的中值CPQ为15.00，与DHC5为22.50，p=0.032)。正畸治疗的开始最初影响CPQ领域“口腔症状”和“功能限制，相对于基线的变化为2.00(p=0.001)，但6个月后再次好转。回归分析表明，患有IOTNDHC5错牙合的儿童对其ORHQoL的影响更大，如CPQ评分比IOTNDHC4错牙合的儿童高7.35分所示（p=0.015）。
结论：在正畸治疗开始时，OHRQoL略有恶化，可能是由于电器的不适和外观。然而,开始正畸治疗6个月后，OHRQoL在严重错牙合（IOTN4和5）患者中再次改善，并接近基线值。
结论：这些结果有助于临床医生更好地了解口腔健康的特定方面，这些方面可能受到不同的咬合不正的影响，从而提高孩子的满意度和整体生活质量。
方法：纳入85例11~14岁需要固定正畸矫治器治疗的患者。孩子们在（T0）之前完成了德语版的儿童感知问卷（CPQ-G-11-14），1个月（T1）和6个月（T2）后开端正畸医治。根据正畸治疗需求指数（IOTN）对错牙合的类型进行分类。
结果：最初类型的错牙合影响了儿童的OHRQoL，而性别和年龄没有。IOTN牙齿健康成分（DHC）对CPQ评分有显著影响（DHC4组的中值CPQ为15.00，与DHC5为22.50，p=0.032)。正畸治疗的开始最初影响CPQ领域“口腔症状”和“功能限制，相对于基线的变化为2.00(p=0.001)，但6个月后再次好转。回归分析表明，患有IOTNDHC5错牙合的儿童对其ORHQoL的影响更大，如CPQ评分比IOTNDHC4错牙合的儿童高7.35分所示（p=0.015）。
结论：在正畸治疗开始时，OHRQoL略有恶化，可能是由于电器的不适和外观。然而,开始正畸治疗6个月后，OHRQoL在严重错牙合（IOTN4和5）患者中再次改善，并接近基线值。
结论：这些结果有助于临床医生更好地了解口腔健康的特定方面，这些方面可能受到不同的咬合不正的影响，从而提高孩子的满意度和整体生活质量。
