关键词: COP1 E3 ubiquitin ligase light molecular basis photomorphogenesis ubiquitination

来  源:   DOI:10.1093/jxb/erae181

Abstract:
COP1 (CONSTITUTIVE PHOTOMORPHOGENIC1), a repressor of seedling photomorphogenesis, is tightly controlled by light. In Arabidopsis, COP1 primarily acts as a part of large E3 ligase complexes and targets key light-signaling factors for ubiquitination and degradation. Upon light perception, the action of COP1 is precisely modulated by active photoreceptors. During seedling development, light plays a predominant role in modulating seedling morphogenesis, including inhibition of hypocotyl elongation, cotyledon opening and expansion, and chloroplast development. These visible morphological changes evidently are resulted from networks of molecular action. In this review, we summarize the current knowledge about the molecular role of COP1 in mediating light-controlled seedling development.
摘要:
COP1(本构光形态发生1),幼苗光形态发生的阻遏物,受到光的严格控制。在拟南芥中,COP1主要作为大型E3连接酶复合物的一部分,并靶向关键的光信号因子进行泛素化和降解。在光线感知下,COP1的作用由活性光感受器精确调节。在幼苗发育过程中,光在调节幼苗形态发生中起着主导作用,包括抑制下胚轴伸长,子叶的开放和扩展,和叶绿体发育。这些可见的形态学变化显然是由分子作用网络引起的。在这次审查中,我们总结了目前有关COP1在介导光控幼苗发育中的分子作用的知识。
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