关键词: Ewing’s sarcoma chemotherapy arthrodesis distal fibula

来  源:   DOI:10.13107/jocr.2024.v14.i04.4350   PDF(Pubmed)

Abstract:
UNASSIGNED: Ewing\'s sarcoma is the second most common primary malignant bone tumor in children and adolescents, after osteosarcoma. It is a rare tumor, with the axial skeleton being the preferred site of development, followed by the long bones. Diagnosis is evoked by imaging and confirmed by histology. Treatment is based on intensive chemotherapy with local surgical treatment in operable forms, and in some cases, radiotherapy. There are only a few sporadic cases in the literature describing distal fibular localization.
UNASSIGNED: We report the case of a 7-year-old child who presented with pain on the lateral aspect of the left ankle without local inflammatory signs. Radiological findings revealed a metaphyseal-diaphyseal osteolytic tissue process of the left fibula, and histology concluded that it was Ewing\'s sarcoma. We proceeded with neoadjuvant polychemotherapy followed by segmental resection of the distal fibula with an anteroexternal tibial rod, plus tibiotalar, and talocalcaneal arthrodesis without recourse to radiotherapy.
UNASSIGNED: The management of Ewing\'s sarcoma is constantly evolving. Its distal fibular location in a growing limb makes it even more difficult. It must be personalized, multidisciplinary, and carried out in specialized centers.
摘要:
尤因肉瘤是儿童和青少年第二常见的原发性恶性骨肿瘤,骨肉瘤后。这是一种罕见的肿瘤,轴向骨架是发展的首选部位,接着是长骨。诊断通过影像学诱发并通过组织学证实。治疗基于强化化疗和可手术形式的局部手术治疗,在某些情况下,放射治疗。文献中只有少数零星病例描述腓骨远端定位。
我们报告了一个7岁儿童的病例,该儿童在左脚踝的外侧出现疼痛,没有局部炎症迹象。放射学发现显示左腓骨的干phy端-干phy端溶骨组织过程,组织学得出结论是尤因肉瘤.我们进行了新辅助综合化疗,然后用胫骨前外棒节段性切除腓骨远端,再加上胫骨,和无放射治疗的距骨关节固定术。
尤因肉瘤的管理在不断发展。它的腓骨远端在生长的肢体中的位置使其变得更加困难。它必须是个性化的,多学科,并在专业中心进行。
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