PDF(Pubmed)
Abstract：
Naevus of Ito and naevus of Ota are benign dermal melanocytoses with similar pathogenic mechanisms of failure in the melanocyte migration to typical locations within the basal layer from neural crest cells and differ in distribution. Bilateral and oral mucosal involvement of naevus of Ota can occur but is infrequent. Naevus of Ito is seldom associated with naevus of Ota and extracutaneous manifestations. A review of the English literature showed 14 cases of naevus of Ota with palatal involvement. None showed bilateral involvement of both naevi with oral involvement. Here we report the case of bilateral naevus of Ito and bilateral naevus of Ota with palatal involvement. A 32-year-old male came to us with naevus of Ito on both sides of his back and naevus of Ota on both sides of his face involving the sclera of both eyes with a bluish lesion along the midline of the hard palate.
摘要：
Ito的Naevus和Ota的Naevus是良性真皮黑素细胞，在黑素细胞从神经c细胞迁移到基底层内典型位置时具有相似的致病机制，并且分布不同。Ota痣的双侧和口腔粘膜受累可能发生，但很少发生。伊藤的痣很少与太田痣和皮外表现有关。对英语文献的回顾显示14例Ota痣受累。没有显示两个naevi的双边参与和口头参与。在这里，我们报告了Ito双侧痣和Ota双侧痣的病例。一名32岁的男性来到我们这里，他的背部两侧是伊藤的痣，脸部两侧是大田的痣，涉及两只眼睛的巩膜，硬腭中线有蓝色病变。
