关键词: case report inguinal lymphadenopathy metastases prostate adenocarcinoma

来  源:   DOI:10.1093/omcr/omae027   PDF(Pubmed)

Abstract:
The presence of lymph node metastases in prostate adenocarcinoma is a poor prognostic sign, and mortality rates are often high. Inguinal lymph node metastases are an unusual presentation of advanced disease, and they can be easily misinterpreted with other diseases. We present a case of a 63-year-old patient with no previous symptoms and signs of prostate disorder with a right-sided inguinal lump and abdominal pain. The CT scan showed right inguinal and retroperitoneal lymphadenopathy. Elevated PSA serum levels, digital rectal examination, and skeletal scintigraphy with 99mTc-MDP favored the diagnosis of metastatic prostate adenocarcinoma. Since the patient denied prostate biopsy, a dissection of the right inguinal nodes was performed. Histopathological findings confirmed metastatic prostate adenocarcinoma. The treatment was hormonal and bisphosphonate therapy, with objective posttreatment improvement. Based on this case, it can be concluded that inguinal and generalized lymphadenopathy are potential initial manifestations of metastatic prostate adenocarcinoma in male patients.
摘要:
前列腺腺癌中淋巴结转移的存在是预后不良的标志,死亡率往往很高。腹股沟淋巴结转移是晚期疾病的不寻常表现,它们很容易被其他疾病误解。我们介绍了一例63岁的患者,先前没有前列腺疾病的症状和体征,右侧腹股沟肿块和腹痛。CT扫描显示右侧腹股沟和腹膜后淋巴结肿大。血清PSA水平升高,直肠指检,99mTc-MDP的骨骼闪烁显像有助于诊断转移性前列腺腺癌。因为病人否认前列腺活检,对右侧腹股沟淋巴结进行了解剖.组织病理学结果证实转移性前列腺腺癌。治疗是激素和双膦酸盐治疗,客观的后处理改善。基于这个案子,可以得出结论,腹股沟和全身淋巴结病是男性患者转移性前列腺腺癌的潜在初始表现。
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