METHODS: Herein, we present the case of an 83-year-old female patient who presented with generalized blistering and erythema during treatment for acute pancreatitis. She was referred to our dermatology department with worsening erythema, although the acute pancreatitis improved. The cause of the erythema was suspected to be drug-induced, infectious, or related to collagen disease; however, the exact cause was unknown. Computed tomography and endoscopic ultrasonography findings revealed a mixed-type intraductal papillary mucinous neoplasm (IPMN). Refractory erythema was suspected to have been caused by a dermadrome due to IPMN. Consequently, she was referred to our department. The main pancreatic duct was dilated along its entire length, and tumor extension was difficult to determine; therefore, a total pancreatectomy was performed. The postoperative course was uneventful, and erythema gradually improved. The histopathological evaluation indicated high-grade dysplasia of the IPMN.
CONCLUSIONS: The patient\'s skin rash, which did not improve with treatment that included high-dose steroids, began to improve after surgery, and the disease was thought to be a dermadrome caused by IPMN.
CONCLUSIONS: We believe that this is the first reported case of IPMN with a dermadrome that resolved after a total pancreatectomy.
方法:这里,我们介绍一例83岁女性患者,在急性胰腺炎治疗期间出现全身性水疱和红斑.她因红斑恶化被转诊到皮肤科,虽然急性胰腺炎好转。红斑的原因怀疑是药物诱发的,传染性,或与胶原蛋白疾病有关;然而,确切原因不明。计算机断层扫描和内窥镜超声检查结果显示为混合型导管内乳头状黏液性肿瘤(IPMN)。难治性红斑被怀疑是由IPMN引起的dermadrome引起的。因此,她被转介到我们部门.主胰管沿其整个长度扩张,和肿瘤的扩展很难确定;因此,进行了全胰腺切除术.术后进展顺利,红斑逐渐好转。组织病理学评估表明IPMN的高度发育不良。
结论:患者的皮疹,包括高剂量类固醇的治疗并没有改善,手术后开始好转,这种疾病被认为是由IPMN引起的。
结论:我们认为这是首例报道的IPMN患者在全胰腺切除术后病情消退。