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Abstract：
OBJECTIVE: To examine the relationship between prenatal alcohol exposure (PAE) and children\'s behavioural and emotional development in a large generalizable sample of women and their children in Aotearoa New Zealand.
METHODS: Using data from the Growing Up in New Zealand longitudinal cohort, we investigated the relationship between maternal PAE and behavioural and emotional development in 8-year-old children. We explored secondary outcomes including measures of language, executive function, academic achievement, and adaptive behaviour.
RESULTS: We found no significant differences in the measures of behavioural and emotional development in children 8 years old based on alcohol consumption. No significant differences in behavioural and emotional development were found based on amount of PAE and when PAE occurred, despite controlling for a range of potential confounding factors, such as neighbourhood deprivation and maternal health measures. PAE was associated with significantly higher scores for parent-rated oral language indicating better oral language. In Māori mothers, PAE was significantly associated with an increased risk of higher scores on two of the Strengths and Difficulties Questionnaire subscales.
CONCLUSIONS: We did not find an association between PAE and behavioural and emotional development in children aged 8 years. PAE and behavioural and emotional development are difficult to measure accurately, and the moderating variables between them are complex. Future analyses will require larger cohorts of mothers and their children using precise measures of PAE and outcomes to enable more precise estimates of association.
METHODS: Using data from the Growing Up in New Zealand longitudinal cohort, we investigated the relationship between maternal PAE and behavioural and emotional development in 8-year-old children. We explored secondary outcomes including measures of language, executive function, academic achievement, and adaptive behaviour.
RESULTS: We found no significant differences in the measures of behavioural and emotional development in children 8 years old based on alcohol consumption. No significant differences in behavioural and emotional development were found based on amount of PAE and when PAE occurred, despite controlling for a range of potential confounding factors, such as neighbourhood deprivation and maternal health measures. PAE was associated with significantly higher scores for parent-rated oral language indicating better oral language. In Māori mothers, PAE was significantly associated with an increased risk of higher scores on two of the Strengths and Difficulties Questionnaire subscales.
CONCLUSIONS: We did not find an association between PAE and behavioural and emotional development in children aged 8 years. PAE and behavioural and emotional development are difficult to measure accurately, and the moderating variables between them are complex. Future analyses will require larger cohorts of mothers and their children using precise measures of PAE and outcomes to enable more precise estimates of association.
摘要：
目的：在Aotearoa新西兰大量可推广的妇女及其子女样本中，研究产前酒精暴露（PAE）与儿童行为和情感发育之间的关系。
方法：使用来自新西兰纵向队列的数据，我们调查了8岁儿童母亲PAE与行为和情绪发育之间的关系.我们探讨了次要结果，包括语言测量，执行功能，学术成就,和适应性行为。
结果：我们发现8岁儿童饮酒后行为和情绪发展指标无显著差异。根据PAE的数量和发生PAE的时间，在行为和情绪发展方面没有发现显着差异。尽管控制了一系列潜在的混杂因素，例如邻里剥夺和产妇保健措施。PAE与父母评分的口语得分明显较高相关，表明口语更好。在毛利母亲中，在两个“优势和困难问卷”分量表上，PAE与较高得分的风险增加显着相关。
结论：我们没有发现8岁儿童PAE与行为和情绪发育之间存在关联。PAE和行为和情绪发展很难准确衡量，它们之间的调节变量很复杂。未来的分析将需要更多的母亲及其子女使用PAE和结果的精确测量，以便能够更精确地估计关联。
方法：使用来自新西兰纵向队列的数据，我们调查了8岁儿童母亲PAE与行为和情绪发育之间的关系.我们探讨了次要结果，包括语言测量，执行功能，学术成就,和适应性行为。
结果：我们发现8岁儿童饮酒后行为和情绪发展指标无显著差异。根据PAE的数量和发生PAE的时间，在行为和情绪发展方面没有发现显着差异。尽管控制了一系列潜在的混杂因素，例如邻里剥夺和产妇保健措施。PAE与父母评分的口语得分明显较高相关，表明口语更好。在毛利母亲中，在两个“优势和困难问卷”分量表上，PAE与较高得分的风险增加显着相关。
结论：我们没有发现8岁儿童PAE与行为和情绪发育之间存在关联。PAE和行为和情绪发展很难准确衡量，它们之间的调节变量很复杂。未来的分析将需要更多的母亲及其子女使用PAE和结果的精确测量，以便能够更精确地估计关联。
