关键词: Constitutional delay of growth and puberty Delayed puberty Hypogonadism

Mesh : Humans Puberty, Delayed / diagnosis etiology Growth Disorders / diagnosis etiology therapy Female Male Diagnosis, Differential Adolescent Child

来  源:   DOI:10.1016/j.ecl.2024.01.007

Abstract:
Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty in both male and female individuals. This article reviews the causes of delayed puberty focusing on CDGP, including new advances in the understanding of the genetics underpinning CDGP, a clinical approach to discriminating CDGP from other causes of delayed puberty, outcomes, as well as current and potential emerging management options.
摘要:
生长和青春期的宪法延迟(CDGP)是男性和女性个体青春期延迟的最常见原因。本文综述了青春期延迟的原因,重点是CDGP,包括对支撑CDGP的遗传学理解的新进展,将CDGP与其他原因引起的青春期延迟区分开来的临床方法,结果,以及当前和潜在的新兴管理选项。
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