Abstract：
Peripheral precocious puberty (PPP) refers to the early onset of sexual maturation that is independent of central nervous system control. The extensive differential diagnosis includes congenital and acquired causes. Presenting features depend on which class of sex steroids is involved, and diagnosis rests on hormonal and, if indicated, imaging and/or genetic studies. Effective treatment exists for nearly all causes of PPP. Ongoing research will advance our therapeutic armamentarium and understanding of the pathophysiologic basis of these conditions.
摘要：
周围性早熟（PPP）是指独立于中枢神经系统控制的性成熟的早期发作。广泛的鉴别诊断包括先天性和获得性原因。呈现特征取决于涉及哪一类性类固醇，诊断取决于荷尔蒙，如果指示，成像和/或遗传研究。几乎所有PPP的原因都有有效的治疗方法。正在进行的研究将促进我们的治疗性医疗设备和对这些疾病的病理生理基础的理解。
