Abstract:
The development of peptide-based materials is one of the most challenging aspects of biomaterials research in recent years. The assembly of peptides is mainly controlled by forces such as hydrogen bonding, hydrophobic interaction, electrostatic interaction, and π-π accumulation. Peptides have unique advantages such as simple structure, easy synthesis, good biocompatibility, non-toxicity, easy modification, etc. These factors make peptides turn into ideal biomedical materials, and they have a broad application prospect in biomedical materials, and thus have received wide attention. In this review, the mechanism and classification of peptide self-assembly and its applications in biomedicine and hydrogels were introduced.
摘要:
肽基材料的开发是近年来生物材料研究中最具挑战性的方面之一。肽的组装主要受氢键等作用力的控制,疏水相互作用,静电相互作用,和π-π积累。多肽具有结构简单、容易合成,良好的生物相容性,无毒性,易于修改,等。这些因素使多肽成为理想的生物医用材料,在生物医用材料中具有广阔的应用前景,因此受到了广泛的关注。在这次审查中,介绍了肽自组装的机理和分类及其在生物医学和水凝胶中的应用。