PDF(Pubmed)
Abstract：
Background and aims: Home parenteral nutrition (HPN) is a life-saving treatment for patients affected by chronic intestinal failure (CIF). Both this clinical condition and its therapy require radical lifestyle modifications, affecting life quality and psychological balance in patients as well as family members. Patient psychological burden has rarely been taken into consideration, not to mention that of caregivers. This study aims to evaluate the levels of anxiety in CIF patients on HPN, and their caregivers, consequently determining their impact on the psychological and physical aspects. Methods: After a brief introductory interview, adult patients on HPN for CIF and their caregivers were asked to fill in the HAMA-A questionnaire. Results: Fifty patients and their respective caregivers were enrolled. Mean HAMA-A scores were similar in patients and caregivers and testified the presence of a mild to severe impact of CIF and HPN in both groups, with a significantly higher impact on female patients and caregivers. After adjusting age, education level, duration of CIF and HPN dependence, and degree of kinship, no differences were revealed in the scores. Conclusions: The study confirms that CIF patients on HPN and their caregivers have a significant anxiety burden independently from the duration of the disease, therefore needing appropriate support.
摘要：
背景和目的：家庭肠外营养（HPN）是一种挽救慢性肠衰竭（CIF）患者生命的治疗方法。这种临床状况及其治疗都需要从根本上改变生活方式，影响患者及家属的生活质量和心理平衡。患者的心理负担很少被考虑，更不用说看护人了。本研究旨在评估HPN患者的焦虑水平，和他们的照顾者，从而确定它们对心理和生理方面的影响。方法：经过简短的介绍性访谈，我们要求接受HPNforCIF的成年患者及其护理人员填写HAMA-A问卷.结果：纳入50例患者及其各自的照顾者。患者和护理人员的平均HAMA-A评分相似，证明了两组中CIF和HPN的轻度至重度影响。对女性患者和护理人员的影响明显更高。调整年龄后,教育水平,CIF和HPN依赖性的持续时间，和亲属关系的程度，评分没有差异.结论：该研究证实，HPN的CIF患者及其照顾者具有显著的焦虑负担，独立于疾病的持续时间，因此需要适当的支持。
