PDF(Pubmed)
Abstract：
OBJECTIVE: The purpose of this study was to investigate whether a clinical effect of Lactobacillus reuteri in supportive periodontal therapy can already be detected with a minimum dose of one tablet a day and a minimum observation and intake period of 3 months.
METHODS: 28 patients with stage III and IV periodontitis undergoing periodontal follow-up were randomly divided into two groups receiving a lozenge containing L. reuteri or a placebo preparation daily for 90 days. After 0, 4, 8, and 12 weeks, the parameters bleeding on probing (BoP), plaque control record (PCR), periodontal probing depth (PPD), and clinical attachment level (CAL) were recorded in the test and control groups.
RESULTS: The results sed a different effect of L. reuteri on the respective patients. In certain patients, clinical parameters worsened or remained largely unchanged. However, in other patients, there were positive effects on the clinical parameters. In the overall analysis, BoP was the only clinical parameter that was statistically significantly reduced.
CONCLUSIONS: The oral administration of one lozenge per day for 3 months with L. reuteri in supportive periodontal therapy might have a positive influence on clinical parameters in supportive periodontal therapy, depending on the individual.
METHODS: 28 patients with stage III and IV periodontitis undergoing periodontal follow-up were randomly divided into two groups receiving a lozenge containing L. reuteri or a placebo preparation daily for 90 days. After 0, 4, 8, and 12 weeks, the parameters bleeding on probing (BoP), plaque control record (PCR), periodontal probing depth (PPD), and clinical attachment level (CAL) were recorded in the test and control groups.
RESULTS: The results sed a different effect of L. reuteri on the respective patients. In certain patients, clinical parameters worsened or remained largely unchanged. However, in other patients, there were positive effects on the clinical parameters. In the overall analysis, BoP was the only clinical parameter that was statistically significantly reduced.
CONCLUSIONS: The oral administration of one lozenge per day for 3 months with L. reuteri in supportive periodontal therapy might have a positive influence on clinical parameters in supportive periodontal therapy, depending on the individual.
摘要：
目的：本研究的目的是研究罗伊氏乳杆菌在支持牙周治疗中的临床效果是否已经可以用每天一片的最小剂量和3个月的最小观察和摄入时间来检测。
方法：将28例进行牙周随访的III期和IV期牙周炎患者随机分为两组，每天接受含罗伊氏乳杆菌的锭剂或安慰剂制剂，共90天。在0、4、8和12周后，探测时出血的参数(BoP)，斑块控制记录（PCR），牙周探诊深度（PPD），记录试验组和对照组的临床依恋水平(CAL)。
结果：结果对各个患者的罗伊氏乳杆菌有不同的作用。在某些患者中,临床参数恶化或基本保持不变.然而,在其他患者中，对临床参数有积极影响.在总体分析中,BoP是统计学上显著降低的唯一临床参数。
结论：在支持牙周治疗中，罗伊氏乳杆菌每天口服一片锭剂，持续3个月，可能对支持牙周治疗的临床参数产生积极影响，取决于个人。
方法：将28例进行牙周随访的III期和IV期牙周炎患者随机分为两组，每天接受含罗伊氏乳杆菌的锭剂或安慰剂制剂，共90天。在0、4、8和12周后，探测时出血的参数(BoP)，斑块控制记录（PCR），牙周探诊深度（PPD），记录试验组和对照组的临床依恋水平(CAL)。
结果：结果对各个患者的罗伊氏乳杆菌有不同的作用。在某些患者中,临床参数恶化或基本保持不变.然而,在其他患者中，对临床参数有积极影响.在总体分析中,BoP是统计学上显著降低的唯一临床参数。
结论：在支持牙周治疗中，罗伊氏乳杆菌每天口服一片锭剂，持续3个月，可能对支持牙周治疗的临床参数产生积极影响，取决于个人。
