PDF(Pubmed)
Abstract：
The incidence of testicular cancer (TC) has been rapidly increasing over the past years. Diagnosis and early treatment have shown good oncological control, guaranteeing the patient different treatment approaches according to histology and tumor stage. Currently, physicians usually prioritize oncological outcomes over sexual outcomes and quality of life, considering as a first aim the overall survival of the patients; however, differently from other neoplasms, quality of life is still strongly affected among TC patients, and sexual outcomes are frequently compromised after each TC treatment. Several studies have suggested that each treatment approach may be associated with sexual dysfunctions, including erectile dysfunction, ejaculatory disorders, fertility issues, and hormonal changes. Since testicular cancer patients are more frequently young men, the subject of this work is substantial and should be analyzed in detail to help specialists in the management of this disease. The aim of the current narrative review is to generally describe every treatment for TC, including surgery, chemotherapy, radiotherapy, and retroperitoneal lymph node dissection, and to establish which sexual dysfunction may be specifically associated with each therapy.
摘要：
在过去的几年中，睾丸癌（TC）的发病率一直在迅速增加。诊断和早期治疗显示良好的肿瘤控制，保证患者根据组织学和肿瘤分期不同的治疗方法。目前,医生通常优先考虑肿瘤结果而不是性结果和生活质量，将患者的总体生存率作为首要目标；然而，不同于其他肿瘤，TC患者的生活质量仍然受到强烈影响，性结局在每次TC治疗后经常受损。几项研究表明，每种治疗方法都可能与性功能障碍有关，包括勃起功能障碍,射精障碍,生育问题,和荷尔蒙的变化。由于睾丸癌患者更多是年轻男性，这项工作的主题是实质性的，应进行详细分析，以帮助专家管理这种疾病。当前叙述性审查的目的是总体描述TC的每种治疗方法，包括手术,化疗,放射治疗,腹膜后淋巴结清扫术,并确定哪些性功能障碍可能与每种疗法具体相关。
