Pombe 中 Gpl1 - Gih35 - Wdr83 复合物的功能障碍影响 DNA 损伤修复因子的剪接 , 从而增加对 DNA 损伤的敏感性。
关键词: DNA damage G-patch protein Gih35 Gpl1 S. pombe Wdr83 pre-mRNA splicing
Mesh : DNA Damage / genetics DNA Repair / genetics Gene Expression Regulation, Fungal RNA Precursors / genetics metabolism RNA Splicing RNA Splicing Factors / metabolism genetics Schizosaccharomyces / genetics metabolism Schizosaccharomyces pombe Proteins / genetics metabolism Spliceosomes / metabolism genetics Multiprotein Complexes / genetics metabolism
来 源:
DOI:10.3390/ijms25084192
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