PDF(Pubmed)
Abstract：
Microbial keratitis in a post-transplant cornea should be considered a distinct entity from microbial keratitis in a non-transplant cornea. Firstly, the use of immunosuppressive treatments and sutures in corneal transplants changes the etiology of keratitis. Secondly, corneal transplant has an impact on corneal biomechanics and structure, which facilitates the spread of infection. Finally, the emergence of lamellar transplants has introduced a new form of keratitis known as interface keratitis. Given these factors, there is a clear need to update our understanding of and management strategies for microbial keratitis following corneal transplantation, especially in the era of lamellar transplants. To address this, a comprehensive review is provided, covering the incidence, risk factors, causes, and timing of microbial keratitis, as well as both clinical and surgical management approaches for its treatment in cases of penetrating and lamellar corneal transplants.
摘要：
移植后角膜中的微生物角膜炎应被视为与非移植角膜中的微生物角膜炎不同的实体。首先,在角膜移植中使用免疫抑制治疗和缝合改变了角膜炎的病因。其次,角膜移植对角膜生物力学和结构有影响，这促进了感染的传播。最后,层状移植的出现引入了一种称为界面角膜炎的新型角膜炎。鉴于这些因素,显然需要更新我们对角膜移植后微生物性角膜炎的理解和管理策略，尤其是在层状移植时代。为了解决这个问题，提供了全面的审查，涵盖发病率，危险因素，原因,和微生物角膜炎的时机，以及在穿透性和板层角膜移植病例中的临床和外科治疗方法。
