PDF(Pubmed)
Abstract：
Background: We aimed to determine whether patients with postural orthostatic tachycardia syndrome (POTS) have sexual dysfunction compared to age-matched healthy controls. Methods: Utilizing online COMPASS-31 to evaluate dysautonomia symptom severity, Beck\'s Depression Inventory Second Edition (BDII), Female Sexual Function (FSF), and International Index of Erection Function (IIEF) questionnaires, we compared sexual function scores in patients with POTS to scores obtained from sex- and age-matched healthy controls via a cross-sectional case-control study. Results: A total of 160 women with POTS, mean age 30.2 ± 7.9 (range 21-50 years), had lower FSF scores than 62 healthy age-matched female controls. IIEF scores in 29 male patients with POTS with a mean age of 30.1 ± 6.0 (range 21-47) were significantly lower than in 27 healthy age-matched male controls. Female POTS patients had significantly lower scores in the sub-domains of desire, arousal, and satisfaction, while male POTS patients had significantly lower scores in erectile and orgasmic function, desire, and satisfaction than healthy controls. Predictive factors of sexual dysfunction were depression in women and age in men. The severity of autonomic symptoms correlated with sexual dysfunction in women, but this effect disappeared after controlling for depression. Conclusions: Compared to healthy controls, women and men with POTS have significant sexual dysfunction, which needs to be considered in the diagnostic and therapeutic approaches as part of comprehensive patient care.
摘要：
背景：我们旨在确定与年龄匹配的健康对照组相比，体位性心动过速综合征（POTS）患者是否存在性功能障碍。方法：利用在线COMPASS-31评估自主神经障碍症状的严重程度，贝克的抑郁症清单第二版(BDII)，女性性功能(FSF)和国际安装功能指数(IIEF)问卷，我们通过一项横断面病例对照研究,将POTS患者的性功能评分与性别和年龄相匹配的健康对照者的评分进行了比较.结果：共有160名妇女患有POTS，平均年龄30.2±7.9（范围21-50岁），FSF得分低于62名健康年龄匹配的女性对照。29名平均年龄为30.1±6.0（范围21-47）的POTS男性患者的IIEF评分显着低于27名健康年龄匹配的男性对照组。女性POTS患者在欲望子领域的得分明显较低，唤醒,和满意，而男性POTS患者在勃起和高潮功能方面得分明显较低，欲望,满意度高于健康对照组。性功能障碍的预测因素是女性抑郁和男性年龄。自主神经症状的严重程度与女性性功能障碍有关，但是这种效果在控制抑郁症后消失了。结论:与健康对照组相比,患有POTS的女性和男性都有明显的性功能障碍，作为全面患者护理的一部分，在诊断和治疗方法中需要考虑这一点。
