PDF(Pubmed)
Abstract：
Chronic rhinosinusitis with nasal polyposis is a common inflammatory condition, with subtypes like aspirin-exacerbated respiratory disease, allergic fungal rhinosinusitis, and central compartment atopic disease sharing a common type 2 inflammatory pathway. Respiratory biologic therapies have been developed that target type 2 inflammation. In this article, we discuss the use of respiratory biologic therapies for nasal polyposis in general, as well as within the various subtypes of nasal polyps. Further, we discuss future roles of novel biologic therapies targeting type 2 inflammation in nasal polyposis.
摘要：
慢性鼻-鼻窦炎伴鼻息肉病是一种常见的炎症,患有阿司匹林加剧的呼吸系统疾病等亚型，过敏性真菌性鼻窦炎,和中央区特应性疾病共享一个共同的2型炎症途径。已经开发了针对2型炎症的呼吸生物疗法。在这篇文章中,我们讨论了呼吸生物疗法对鼻息肉的一般使用，以及鼻息肉的各种亚型。Further,我们讨论了针对鼻息肉病2型炎症的新型生物疗法的未来作用。
