PDF(Pubmed)
Abstract：
Addressing non-unions involves stabilizing the affected area through osteosynthesis and improving bone biology using bone grafts. However, there is no consensus on the optimal treatment method. This study aims to compare outcomes of non-union surgery using conventional treatment methods (metal hardware ± graft) versus osteosynthesis with the human allogeneic cortical bone screw (Shark Screw®) alone or in combination with a metallic plate. Thirty-four patients underwent conventional treatment, while twenty-eight cases received one or more Shark Screws®. Patient demographics, bone healing, time to bone healing, and complications were assessed. Results revealed a healing rate of 96.4% for the Shark Screw® group, compared to 82.3% for the conventionally treated group. The Shark Screw® group exhibited a tendency for faster bone healing (9.4 ± 3.2 vs. 12.9 ± 8.5 weeks, p = 0.05061). Hardware irritations led to six metal removals in the conventional group versus two in the Shark Screw® group. The Shark Screw® emerges as a promising option for personalized non-union treatment in the foot, ankle, and select lower leg cases, facilitating effective osteosynthesis and grafting within a single construct and promoting high union rates, low complications, and a rapid healing process.
摘要：
解决不愈合涉及通过骨合成来稳定受影响的区域并使用骨移植物改善骨生物学。然而,关于最佳治疗方法尚无共识。这项研究旨在比较使用常规治疗方法（金属硬件±移植物）与单独使用人同种异体皮质骨螺钉（SharkScrew®）或与金属板结合使用的骨合成术的不愈合手术的结果。34例患者接受常规治疗,而28例收到一个或多个鲨鱼螺丝®。患者人口统计学，骨愈合，骨头愈合的时间，并对并发症进行了评估。结果显示SharkScrew®组的治愈率为96.4%，与常规治疗组的82.3%相比。SharkScrew®组表现出更快的骨骼愈合趋势（9.4±3.2与12.9±8.5周，p=0.05061)。硬件刺激导致常规组中的六种金属去除，而SharkScrew®组中的两种金属去除。SharkScrew®成为一种有希望的选择，用于脚部的个性化不愈合治疗，脚踝,选择小腿病例，在单一结构中促进有效的骨合成和移植，并促进高结合率，低并发症,一个快速的愈合过程。
