PDF(Pubmed)
Abstract：
This review delves into the possible connection between periodontitis and negative pregnancy outcomes, such as preeclampsia and preterm birth. It highlights the potential influence of an unidentified microbial factor on preeclampsia and the effects of inflammatory responses on the rate of preterm births. Furthermore, it underscores the prevalent occurrence of oral ailments within the populace and their significant repercussions on quality of life. Hormonal fluctuations during pregnancy may exacerbate oral conditions such as pregnancy gingivitis and periodontitis, necessitating bespoke therapeutic approaches that take into account potential fetal ramifications. Periodontal disease, characterized by microbial attack and inflammatory response, results in tissue destruction and tooth loss. The oral cavity\'s susceptibility to bacterial colonization, which is primarily due to its role as a site for food intake, is highlighted. Furthermore, research indicates a correlation between inflammatory responses and factors such as prostaglandin E2 and IL-1β, and preterm birth. Therapeutic interventions are a focus of international research, with efforts being aimed at optimizing outcomes through larger studies involving pregnant women.
摘要：
这篇综述探讨了牙周炎与阴性妊娠结局之间的可能联系。如先兆子痫和早产。它强调了未知的微生物因子对先兆子痫的潜在影响以及炎症反应对早产率的影响。此外，它强调了口腔疾病在民众中的普遍发生及其对生活质量的重大影响。怀孕期间的荷尔蒙波动可能会加剧口腔疾病，如妊娠牙龈炎和牙周炎，需要考虑到潜在的胎儿分支的定制治疗方法。牙周病,以微生物攻击和炎症反应为特征，导致组织破坏和牙齿脱落。口腔对细菌定植的敏感性，这主要是由于它作为食物摄入场所的作用，突出显示。此外，研究表明炎症反应与前列腺素E2和IL-1β等因素之间存在相关性，和早产。治疗干预是国际研究的重点，努力通过涉及孕妇的更大研究来优化结局。
