PDF(Pubmed)
Abstract：
BACKGROUND: Prostate cancer is a prevalent cancer among men. Multiparametric ultrasound [mpUS] is a diagnostic instrument that uses various types of ultrasounds to diagnose it. This systematic review aims to evaluate the performance of different parametric ultrasounds in diagnosing prostate cancer by associating with radical prostatectomy specimens.
METHODS: A review was performed on various ultrasound parameters using five databases. Systematic review tools were utilized to eliminate duplicates and identify relevant results. Reviewers used the Quality Assessment of Diagnostic Accuracy Results [QUADAS-2] to evaluate the bias and applicability of the study outcomes.
RESULTS: Between 2012 and 2023, eleven studies were conducted to evaluate the performance of the different ultrasound parametric procedures in detecting prostate cancer using grayscale TRUS, SWE, CEUS, and mpUS. The high sensitivity of these procedures was found at 55%, 88.6%, 81%, and 74%, respectively. The specificity of these procedures was found to be 93.4%, 97%, 88%, and 59%, respectively. This high sensitivity and specificity may be associated with the large lesion size. The studies revealed that the sensitivity of these procedures in diagnosing clinically significant prostate cancer was 55%, 73%, 70%, and 74%, respectively, while the specificity was 61%, 78.2%, 62%, and 59%, respectively.
CONCLUSIONS: The mpUS procedure provides high sensitivity and specificity in PCa detection, especially for clinically significant prostate cancer.
METHODS: A review was performed on various ultrasound parameters using five databases. Systematic review tools were utilized to eliminate duplicates and identify relevant results. Reviewers used the Quality Assessment of Diagnostic Accuracy Results [QUADAS-2] to evaluate the bias and applicability of the study outcomes.
RESULTS: Between 2012 and 2023, eleven studies were conducted to evaluate the performance of the different ultrasound parametric procedures in detecting prostate cancer using grayscale TRUS, SWE, CEUS, and mpUS. The high sensitivity of these procedures was found at 55%, 88.6%, 81%, and 74%, respectively. The specificity of these procedures was found to be 93.4%, 97%, 88%, and 59%, respectively. This high sensitivity and specificity may be associated with the large lesion size. The studies revealed that the sensitivity of these procedures in diagnosing clinically significant prostate cancer was 55%, 73%, 70%, and 74%, respectively, while the specificity was 61%, 78.2%, 62%, and 59%, respectively.
CONCLUSIONS: The mpUS procedure provides high sensitivity and specificity in PCa detection, especially for clinically significant prostate cancer.
摘要：
背景：前列腺癌是男性中普遍存在的癌症。多参数超声[mpUS]是一种使用各种类型的超声对其进行诊断的诊断仪器。本系统综述旨在通过与根治性前列腺切除术标本相关联，评估不同参数超声在诊断前列腺癌中的性能。
方法：使用五个数据库对各种超声参数进行了综述。系统审查工具被用来消除重复和确定相关的结果。评审人员使用诊断准确性结果质量评估[QUADAS-2]来评估研究结果的偏倚和适用性。
结果：在2012年至2023年之间，进行了11项研究，以评估使用灰度TRUS检测前列腺癌的不同超声参数程序的性能，SWE,CEUS,和MPUS。这些程序的高灵敏度为55％，88.6%,81%,74%,分别。发现这些程序的特异性为93.4％，97%,88%,59%,分别。这种高灵敏度和特异性可能与较大的病变大小有关。研究表明，这些程序诊断有临床意义的前列腺癌的敏感性为55％，73%,70%,74%,分别,而特异性为61%，78.2%,62%,59%,分别。
结论：mpUS程序在PCa检测中提供了高灵敏度和特异性，特别是临床上有意义的前列腺癌。
方法：使用五个数据库对各种超声参数进行了综述。系统审查工具被用来消除重复和确定相关的结果。评审人员使用诊断准确性结果质量评估[QUADAS-2]来评估研究结果的偏倚和适用性。
结果：在2012年至2023年之间，进行了11项研究，以评估使用灰度TRUS检测前列腺癌的不同超声参数程序的性能，SWE,CEUS,和MPUS。这些程序的高灵敏度为55％，88.6%,81%,74%,分别。发现这些程序的特异性为93.4％，97%,88%,59%,分别。这种高灵敏度和特异性可能与较大的病变大小有关。研究表明，这些程序诊断有临床意义的前列腺癌的敏感性为55％，73%,70%,74%,分别,而特异性为61%，78.2%,62%,59%,分别。
结论：mpUS程序在PCa检测中提供了高灵敏度和特异性，特别是临床上有意义的前列腺癌。
