METHODS: To evaluate the association between HIV infection in experienced patients and vascular pathology, we performed a cross-sectional study, observing 1006 patients, 380 HIV+ enrolled in the Archiprevaleat cohort, and 626 HIV- as a control group. All patients underwent a Doppler scan of the supra-aortic vessels. We compared the prevalence of IMT > 1.0 mm and plaques in the two groups.
RESULTS: Patients in the HIV+ group were younger than those in the HIV- group, with a lower prevalence of hypertension and diabetes and higher dyslipidemia. The prevalence of plaques in strata of age was higher in the HIV+ group than in the HIV- group and was associated with the length of ART exposure.
CONCLUSIONS: Our cross-sectional, retrospective study shows that HIV+ experienced patients are at greater risk of IMT and atheromatous plaques compared to HIV-. The risk is associated with being HIV+ and with the length of ART exposure. This finding may be useful in preventing cardiovascular risk.
方法:为了评估有经验患者的HIV感染与血管病理学之间的关系,我们进行了横断面研究,观察1006名患者,380名HIV+在Archiprevaleat队列中注册,和626HIV-作为对照组。所有患者均接受了主动脉上血管的多普勒扫描。我们比较了两组中IMT>1.0mm和斑块的患病率。
结果:HIV+组患者比HIV-组患者年轻,高血压和糖尿病患病率较低,血脂异常较高。年龄层次中的斑块患病率在HIV+组中高于HIV-组,并且与ART暴露时间有关。
结论:我们的横截面,回顾性研究显示,与HIV-患者相比,HIV+患者发生IMT和粥样斑块的风险更高.该风险与HIV+和ART暴露时间有关。这一发现可能有助于预防心血管风险。