PDF(Pubmed)
Abstract：
This study aimed to investigate the effects of intranasal air-puffing on cognitive impairments and brain cortical activity following one night of partial sleep deprivation (PSD) in adults. A total of 26 healthy adults underwent the numerical Stroop test (NST) and electroencephalography (EEG) before and after one night of PSD. Following PSD, subjects in the treatment group (n = 13) received nasal air-puffs (5 Hz, 3 min) before beginning the NST and EEG recording. Administration of nasal air-puffs in the treatment group restored the PSD-induced increase in error rate and decrease in reaction time and missing rate in the NST. Intranasal air-puffs recovered the PSD-induced augmentation of delta and theta power and the reduction of beta and gamma power in the EEG, particularly in the frontal lobes. Intranasal air-puffing also almost reversed the PSD-induced decrease in EEG signal complexity. Furthermore, it had a restorative effect on PSD-induced alteration in intra-default mode network functional connectivity in the beta and gamma frequency bands. Rhythmic nasal air-puffing can mitigate acute PSD-induced impairments in cognitive functions. It exerts part of its ameliorating effect by restoring neuronal activity in cortical brain areas involved in cognitive processing.
摘要：
这项研究旨在研究成人部分睡眠剥夺（PSD）一晚后鼻内吹气对认知障碍和大脑皮层活动的影响。共有26名健康成年人在PSD的一个晚上之前和之后进行了数值Stroop测试（NST）和脑电图（EEG）。PSD之后,治疗组(n=13)的受试者接受了鼻腔通气(5Hz，3分钟），然后开始NST和EEG记录。治疗组的鼻腔通气恢复了PSD引起的错误率增加，反应时间和NST缺失率降低。鼻内吹气恢复了PSD引起的δ和θ功率的增加以及EEG中β和γ功率的降低，尤其是额叶。鼻内吸气也几乎逆转了PSD引起的EEG信号复杂性降低。此外，它对PSD诱导的β和γ频段默认模式内网络功能连通性改变有恢复作用.有节奏的鼻腔充气可以减轻PSD引起的急性认知功能损害。它通过恢复参与认知加工的大脑皮层区域的神经元活动来发挥部分改善作用。
