PDF(Pubmed)
Abstract：
BACKGROUND: Although the Coxiella burnetii infection has been investigated in dogs, its role in human transmission remains to be fully established, particularly in close and daily human-dog contact settings, such as in Police K-9 Units.
METHODS: Accordingly, this study aimed to assess anti-C. burnetii antibodies in clinically healthy police officers by an in-house indirect immunofluorescence assay (IFA), and working dogs by a commercial IFA Kit, from the State Special Operations Battalion, Paraná, Southern Brazil.
RESULTS: Overall, 1/18 (5.5%) police officers and 9/30 (30.0%; CI 95% 16.66-47.88) dogs tested seropositive to anti-C. burnetii IgG antibodies.
CONCLUSIONS: To date, this is the highest prevalence of Q fever seropositivity among military dogs worldwide. Despite the low sampling rate, a statistically significant association was found between seropositivity and female dogs (p = 0.0492). Further studies with larger sample sizes should be conducted to establish the prevalence of Q Fever in other Brazilian K-9 Units. In summary, this study is the first to conduct a concomitant serosurvey of police officers and working dogs, and its findings should be considered a warning for cross-exposure and transmission of Coxiella burnetii among Police K-9 Units in Brazil and worldwide.
METHODS: Accordingly, this study aimed to assess anti-C. burnetii antibodies in clinically healthy police officers by an in-house indirect immunofluorescence assay (IFA), and working dogs by a commercial IFA Kit, from the State Special Operations Battalion, Paraná, Southern Brazil.
RESULTS: Overall, 1/18 (5.5%) police officers and 9/30 (30.0%; CI 95% 16.66-47.88) dogs tested seropositive to anti-C. burnetii IgG antibodies.
CONCLUSIONS: To date, this is the highest prevalence of Q fever seropositivity among military dogs worldwide. Despite the low sampling rate, a statistically significant association was found between seropositivity and female dogs (p = 0.0492). Further studies with larger sample sizes should be conducted to establish the prevalence of Q Fever in other Brazilian K-9 Units. In summary, this study is the first to conduct a concomitant serosurvey of police officers and working dogs, and its findings should be considered a warning for cross-exposure and transmission of Coxiella burnetii among Police K-9 Units in Brazil and worldwide.
摘要：
背景：尽管已经在狗中研究了伯氏柯西氏菌感染，其在人类传播中的作用仍有待充分确立，特别是在近距离和日常的人狗接触环境中，例如警察K-9部队。
方法：因此，本研究旨在评估抗C.通过内部间接免疫荧光测定法（IFA），在临床健康的警察中检测到的Burnetii抗体，和商业IFA工具包的工作犬，来自国家特种作战营,巴拉那,巴西南部。
结果：总体而言，1/18（5.5％）警察和9/30（30.0％；CI95％16.66-47.88）狗的抗C血清呈阳性。BurnetiiIgG抗体。
结论：迄今为止，这是全球军犬中Q热血清阳性的最高患病率。尽管采样率低，血清阳性与雌性犬之间存在统计学上的显著关联(p=0.0492).应进行更大样本量的进一步研究，以确定其他巴西K-9单位的Q热患病率。总之,这项研究是第一个同时对警察和工作犬进行血清调查的研究，其调查结果应被视为对巴西和全球警察K-9部队交叉暴露和传播伯内蒂柯西拉的警告。
方法：因此，本研究旨在评估抗C.通过内部间接免疫荧光测定法（IFA），在临床健康的警察中检测到的Burnetii抗体，和商业IFA工具包的工作犬，来自国家特种作战营,巴拉那,巴西南部。
结果：总体而言，1/18（5.5％）警察和9/30（30.0％；CI95％16.66-47.88）狗的抗C血清呈阳性。BurnetiiIgG抗体。
结论：迄今为止，这是全球军犬中Q热血清阳性的最高患病率。尽管采样率低，血清阳性与雌性犬之间存在统计学上的显著关联(p=0.0492).应进行更大样本量的进一步研究，以确定其他巴西K-9单位的Q热患病率。总之,这项研究是第一个同时对警察和工作犬进行血清调查的研究，其调查结果应被视为对巴西和全球警察K-9部队交叉暴露和传播伯内蒂柯西拉的警告。
