PDF(Pubmed)
Abstract：
The most common pesticide agents are organophosphates and phosphides, aluminum phosphide (ALP) in particular. ALP is a major cause of suicidal poisoning in many countries. In other countries, the problem of accidental, mainly occupational-related, poisoning is also real and actual. Almost two thirds of individuals in poisoning cases have died. This case report describes a case of a patient with accidental ALP intoxication. The origin of the poisoning was the fumigation of stored grain in an agricultural building adjacent to the building in which patient was temporarily housed, while both buildings were connected by an underground corridor, through which the released poison gas penetrated. The case was originally presented by the rescuers as well as healthcare professionals of the local hospital as carbon monoxide intoxication, which has a similar symptomatology as ALP intoxication. The patient was treated comprehensively, including using the HBOT method, which is very unique in the case of phosphine intoxication in human medicine, with an excellent final clinical outcome. This was the first described case of HBOT for ALP intoxication in clinical medicine, although the HBOT indication itself became a coincidence in this case. Further studies must be undertaken to demonstrate the effectiveness of HBOT in treating patients with ALP poisoning.
摘要：
最常见的杀虫剂是有机磷酸酯和磷化物，特别是磷化铝(ALP)。ALP是许多国家自杀中毒的主要原因。在其他国家,偶然的问题，主要与职业有关，中毒也是真实的。近三分之二的中毒病例已经死亡。该病例报告描述了一例患有急性ALP中毒的患者。中毒的起源是在临时安置病人的建筑物附近的农业建筑物中熏蒸储存的谷物，虽然这两座建筑都是通过地下通道相连的，释放的毒气穿透。该病例最初由救援人员和当地医院的医疗保健专业人员介绍为一氧化碳中毒，与ALP中毒有相似的症状。患者得到全面治疗，包括使用HBOT方法，在人类医学中磷化氢中毒的情况下，这是非常独特的，具有出色的最终临床结果。这是在临床医学中描述的首例HBOT用于ALP中毒的病例，尽管HBOT指示本身在这种情况下成为一个巧合。必须进行进一步的研究以证明HBOT治疗ALP中毒患者的有效性。
