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Abstract：
Covalent organic frameworks (COFs) are porous crystals that have high designability and great potential in designing, encapsulating, and immobilizing nanozymes. COF nanozymes have also attracted extensive attention in analyte sensing and detection because of their abundant active sites, high enzyme-carrying capacity, and significantly improved stability. In this paper, we classify COF nanozymes into three types and review their characteristics and advantages. Then, the synthesis methods of these COF nanozymes are introduced, and their performances are compared in a list. Finally, the applications of COF nanozymes in environmental analysis, food analysis, medicine analysis, disease diagnosis, and treatment are reviewed. Furthermore, we also discuss the application prospects of COF nanozymes and the challenges they face.
摘要：
共价有机骨架（COFs）是多孔晶体，具有很高的可设计性和巨大的设计潜力，封装，和固定纳米酶。COF纳米酶因其丰富的活性位点在分析物传感和检测中也引起了广泛的关注,高酶携带能力，稳定性显著提高。在本文中,我们将COF纳米酶分为三种类型，并回顾了它们的特点和优势。然后，介绍了这些COF纳米酶的合成方法,并在列表中比较他们的表现。最后,COF纳米酶在环境分析中的应用，食物分析,医学分析,疾病诊断,和治疗进行审查。此外，我们还讨论了COF纳米酶的应用前景以及它们面临的挑战。
