PDF(Pubmed)
Abstract：
This systematic review with meta-analysis aimed to explore the association between formal social participation and cognitive function in middle-aged and older adults using data from longitudinal studies. A comprehensive search was conducted in Scopus, PubMed, and Web of Science for longitudinal studies that assessed the association between formal social participation and cognitive function in middle-aged and older adults published between January 2010 to 19 August 2022. Risk of bias was judged using the RoBANS tool. Meta-analysis using a random-effects model was computed with odds ratio (OR) and 95% confidence interval (CI) for cognitive decline probability. Sensitivity analyses were made to explore any changes to the pooled statistical heterogeneity and pooled effect size. Certainty of evidence was judged using the GRADE framework. We included 15 studies comprising 136,397 participants from 5 countries. Meta-analyses showed that formal social participation was associated with reduced cognitive decline (OR = 0.78, 95% CI 0.75-0.82, p < 0.001), with very low certainty of evidence. Formal social participation appears to enhance cognition in middle-aged and older adults, but further high-quality research is needed given the very low certainty of evidence.
摘要：
这项系统的荟萃分析综述旨在使用纵向研究的数据探讨中老年人的正式社会参与与认知功能之间的关系。在Scopus进行了全面搜索，PubMed,和WebofScience在2010年1月至2022年8月19日期间发表的评估中老年人正式社会参与与认知功能之间关联的纵向研究。使用RoBANS工具判断偏倚风险。使用随机效应模型的荟萃分析计算了认知下降概率的比值比（OR）和95％置信区间（CI）。进行敏感性分析以探索合并的统计异质性和合并效应大小的任何变化。使用等级框架判断证据的确定性。我们纳入了15项研究，包括来自5个国家的136,397名参与者。Meta分析显示，正式的社会参与与认知功能下降减少相关（OR=0.78，95％CI0.75-0.82，p<0.001）。证据的确定性很低。正式的社会参与似乎增强了中老年人的认知，但鉴于证据的确定性非常低,需要进一步的高质量研究.
