PDF(Pubmed)
Abstract：
Glutaraldehyde (GA), a potent disinfectant and sterilizing agent extensively used in healthcare settings, has garnered attention for its association with contact dermatitis. This occupational skin condition, often induced by repeated exposure to GA, poses significant challenges to the well-being of healthcare professionals and patients alike. Understanding the causes, symptoms, and preventive measures against GA-induced contact dermatitis is essential for promoting a safe and healthy working environment in healthcare facilities. A 28-year-old female presented with a severe burning sensation and dark brown patches in the lower chin region, one day following root canal treatment. Based on the characteristic appearance of patches and the typical burning sensation associated with an allergic reaction, a diagnosis of acute contact dermatitis was made. Patch testing by an expert dermatologist confirmed that the patient was allergic to GA. GA, a popular commercial germicidal product, is widely used as a cold sterilizing agent for operative dental instruments. The patient developed a reaction as the endodontic files used during the root canal procedure were cold sterilized with 2% GA. The lesion experienced significant improvement and ultimately healed following the administration of corticosteroids and antihistamines. This report concerns a case of GA-induced contact dermatitis. As GA is being used more widely, particularly in dental clinics, this case was of interest and is reported in the safety interest of patients and clinicians.
摘要：
戊二醛(GA),一种广泛用于医疗机构的有效消毒剂和灭菌剂，因其与接触性皮炎的关系而受到关注。这种职业性皮肤状况，通常由反复暴露于GA引起，对医疗保健专业人员和患者的福祉提出了重大挑战。了解原因，症状,针对GA引起的接触性皮炎的预防措施对于在医疗机构中促进安全和健康的工作环境至关重要。一名28岁的女性表现出严重的灼烧感和下下巴区域的深棕色斑点，根管治疗后一天。根据斑块的特征性外观和与过敏反应相关的典型烧灼感，诊断为急性接触性皮炎。专家皮肤科医生的贴片测试证实患者对GA过敏。GA,一种流行的商业杀菌产品，广泛用作手术牙科器械的冷消毒剂。当在根管手术过程中使用的牙髓文件用2％GA冷灭菌时，患者出现了反应。在施用皮质类固醇和抗组胺剂后,病变经历显著改善并最终愈合。本报告涉及一例GA诱发的接触性皮炎。随着GA的使用越来越广泛，特别是在牙科诊所，该病例引起了人们的关注,并报告了患者和临床医生的安全性.
