关键词: Melanoma nail bed pigmented subungual

Mesh : Humans Melanoma / pathology surgery therapy diagnosis Skin Neoplasms / pathology surgery therapy diagnosis Hand / surgery pathology Sentinel Lymph Node Biopsy

来  源:   DOI:10.1177/17531934241245028

Abstract:
Malignant melanoma is the leading cause of death from skin cancer. In spite of significant advances in the management of melanoma with the advent of sentinel lymph node biopsy (SLNB) and adjuvant oncological therapies, the death rate continues to increase worldwide. Melanoma in the hand poses additional diagnostic and management challenges. Consequently, these tend to present at a later stage and are associated with a poorer prognosis. It is imperative that hand surgeons treat any pigmented hand lesion with suspicion to ensure rapid diagnosis and treatment. This article outlines the presentation of melanoma, and how to investigate suspicious pigmented lesions of the hand and digits. It guides hand surgeons in their approach to melanoma of the hand, outlining the multidisciplinary team approach as well as current standard surgical and reconstructive options to optimize outcomes.
摘要:
恶性黑色素瘤是皮肤癌死亡的主要原因。尽管随着前哨淋巴结活检(SLNB)和辅助肿瘤治疗的出现,黑色素瘤的管理取得了重大进展,全球死亡率继续上升。手中的黑色素瘤带来了额外的诊断和管理挑战。因此,这些倾向于在晚期阶段出现,并且与较差的预后相关.手外科医师必须怀疑任何色素性手部病变,以确保快速诊断和治疗。这篇文章概述了黑色素瘤的表现,以及如何调查手部和手指的可疑色素性病变。它指导手外科医生治疗手部黑色素瘤,概述了多学科团队方法以及当前的标准手术和重建方案,以优化结果。
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