Abstract：
Thunderclap headache is a sudden severe headache with onset to peak within one minute. Multiple excruciating, short-lived thunderclap headaches over a few days to weeks are highly suggestive of reversible cerebral vasoconstriction syndrome (RCVS). RCVS can be primary or secondary to several factors, but it is rarely described after neuro-endovascular procedures using onyx material. A 10-year-old child presented with RCVS heralded by recurrent thunderclap headache following endovascular embolization of pial arteriovenous malformation with onyx material (contains organic solvent dimethyl sulfoxide). Dimethyl sulfoxide is an angiotoxic material that can cause dysregulation of cerebral vascular tone triggering reversible cerebral vasoconstriction syndrome. Recurrent thunderclap headache after embolization procedures using onyx material should prompt for the diagnosis of reversible cerebral vasoconstriction syndrome.
摘要：
雷击头痛是一种突然的严重头痛，在一分钟内发作至高峰。多重痛苦，几天到几周的短暂雷击性头痛高度提示可逆性脑血管收缩综合征（RCVS）。RCVS可以是几个因素的主要或次要因素，但是在使用玛瑙材料进行神经血管内手术后很少描述。一名10岁的儿童在用玛瑙材料（含有有机溶剂二甲基亚砜）血管内栓塞膜动静脉畸形后，出现RCVS，预示着雷击性头痛。二甲基亚砜是一种血管毒性物质，可引起脑血管张力失调，触发可逆性脑血管收缩综合征。使用玛瑙材料进行栓塞手术后复发性雷击头痛应提示诊断可逆性脑血管收缩综合征。
