关键词: Axial flow blood pump Intravascular device Micro-axial pump VAD pLVAD

来  源:   DOI:10.1007/s10047-024-01433-3

Abstract:
The utilization of a minimally invasively placed catheter-mounted intravascular micro-axial flow blood pump (IMFBP) is increasing in the population with advanced heart failure. The current development of IMFBPs dates back around the 1990s, namely the Hemopump with a wire-drive system and the Valvopump with a direct-drive system. The wire-drive IMFBPs can use a brushless motor in an external console unit to transmit rotational force through the drive wire rotating the impeller inside the body. The direct-drive IMFBPs require an ultra-miniature and high-power brushless motor. Additionally, the direct-drive system necessitates a mechanism to protect against blood immersion into the motor. Therefore, the direct-drive IMFBPs can be categorized into two types of devices: those with seal mechanisms or those with sealless mechanisms using magnetically coupling. The IMFBPs can be classified into two groups depending on their purpose. One group is for cardiogenic shock following a heart attack or for use in high-risk percutaneous coronary intervention (PCI), and the other group serves the purpose of acute decompensated heart failure. Both direct-drive IMFBPs and wire-drive IMFBPs have their own advantages and disadvantages, and efforts are being made to develop and improve, and clinically implement them, leveraging their own strengths. In addition, there is a possibility that innovative new devices may be invented. For researchers in the field of artificial heart development, IMFBPs offer a new area of research and development, providing a novel treatment option for severe heart failure.
摘要:
在患有晚期心力衰竭的人群中,微创放置导管安装的血管内微轴流血泵(IMFBP)的利用率正在增加。IMFBP的当前发展可以追溯到1990年代左右,即带有线驱动系统的Hemopump和带有直接驱动系统的Valvopump。线驱动IMFBP可以在外部控制台单元中使用无刷电机,以通过驱动线传递旋转力,使叶轮在主体内部旋转。直接驱动IMFBP需要超微型和大功率无刷电机。此外,直接驱动系统需要一种防止血液浸入电机的机构。因此,直接驱动IMFBP可以分为两种类型的设备:具有密封机构的设备或具有使用磁耦合的无密封机构的设备。IMFBP可以根据其目的分为两组。一组用于心脏病发作后的心源性休克或用于高危经皮冠状动脉介入治疗(PCI),另一组为急性失代偿性心力衰竭的目的。直驱IMFBP和线驱IMFBP各有优缺点,正在努力发展和改进,并在临床上实施它们,利用自己的优势。此外,创新的新设备有可能被发明出来。对于人造心脏发育领域的研究人员来说,IMFBP提供了一个新的研究和开发领域,为严重心力衰竭提供了一种新的治疗选择。
公众号