关键词: Environment and public health Health status Mortality Nitric oxide UVR

来  源:   DOI:10.1016/j.jid.2023.12.027

Abstract:
UVR is a skin carcinogen, yet no studies link sun exposure to increased all-cause mortality. Epidemiological studies from the United Kingdom and Sweden link sun exposure with reduced all-cause, cardiovascular, and cancer mortality. Vitamin D synthesis is dependent on UVB exposure. Individuals with higher serum levels of vitamin D are healthier in many ways, yet multiple trials of oral vitamin D supplementation show little benefit. Growing evidence shows that sunlight has health benefits through vitamin D-independent pathways, such as photomobilization of nitric oxide from cutaneous stores with reduction in cardiovascular morbidity. Sunlight has important systemic health benefit as well as risks.
摘要:
UVR是一种皮肤癌,然而,没有研究将日晒暴露与全因死亡率的增加联系起来。来自英国和瑞典的流行病学研究将阳光照射与减少所有原因联系起来,心血管,和癌症死亡率。维生素D的合成依赖于UVB的暴露。血清维生素D水平较高的人在许多方面更健康,然而,口服维生素D补充剂的多项试验显示益处不大.越来越多的证据表明,阳光通过不依赖维生素D的途径对健康有益,例如从皮肤储存中吸收一氧化氮,降低心血管发病率。阳光具有重要的全身健康益处和风险。
公众号