关键词: Brain fog COVID-19 encephalopathy Case report Cerebral infarction Hemorrhagic transformation Novel coronavirus infection Subdural effusion

来  源:   DOI:10.12998/wjcc.v12.i10.1799   PDF(Pubmed)

Abstract:
BACKGROUND: The precise mechanism by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impacts the central nervous system remains unclear, with manifestations spanning from mild symptoms (e.g., olfactory and gustatory deficits, hallucinations, and headache) to severe complications (e.g., stroke, seizures, encephalitis, and neurally demyelinating lesions). The occurrence of single-pass subdural effusion, as described below, is extremely rare.
METHODS: A 56-year-old male patient presented with left-sided limb weakness and slurred speech as predominant clinical symptoms. Through comprehensive imaging and diagnostic assessments, he was diagnosed with cerebral infarction complicated by hemorrhagic transformation affecting the right frontal, temporal, and parietal regions. In addition, an intracranial infection with SARS-CoV-2 was identified during the rehabilitation process; consequently, an idiopathic subdural effusion developed. Remarkably, the subdural effusion underwent absorption within 6 d, with no recurrence observed during the 3-month follow-up.
CONCLUSIONS: Subdural effusion is a potentially rare intracranial complication associated with SARS-CoV-2 infection.
摘要:
背景:严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)影响中枢神经系统的确切机制尚不清楚,表现为轻度症状(例如,嗅觉和味觉缺陷,幻觉,和头痛)至严重并发症(例如,中风,癫痫发作,脑炎,和神经脱髓鞘病变)。单程硬膜下积液的发生,如下所述,极为罕见。
方法:一名56岁男性患者以左侧肢体无力和言语不清为主要临床症状。通过全面的成像和诊断评估,他被诊断为脑梗死并伴有右额叶出血性转化,temporal,和顶叶区域。此外,在康复过程中发现了SARS-CoV-2的颅内感染;因此,特发性硬膜下积液。值得注意的是,硬膜下积液在6d内吸收,在3个月的随访中没有观察到复发。
结论:硬膜下积液是一种与SARS-CoV-2感染相关的潜在罕见颅内并发症。
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