UNASSIGNED: The distribution of nerve fibers, and blood and lymphatic vessels was examined in whole-mount auricular skins of mice by combining the biomarkers protein gene product 9.5, cluster of differentiation 31, and lymphatic-vessel endothelial hyaluronan receptor-1 following tissue-clearing treatment with multiple immunofluorescent staining.
UNASSIGNED: The labeled nerve fibers, and the blood and lymphatic vessels were distributed extensively in the inner and outer parts of the auricular skin. Auricular nerves aligning with blood vessels ran from the basal region to the peripheral region and crossed over lymphatic vessels, thus forming the neural, vascular, and lymphatic networks.
UNASSIGNED: As these are important tissue components of auricular skin, this result implies that the auricular nerve fibers, and blood and lymphatic vessels may coordinate with each other to respond directly to auricular stimulation.
■神经纤维的分布,通过结合生物标志物蛋白基因产物9.5,分化簇31和淋巴管内皮透明质酸受体-1,在多次免疫荧光染色清除组织处理后,在小鼠的全耳皮肤中检查了血液和淋巴管。
■标记的神经纤维,血液和淋巴管广泛分布在耳廓皮肤的内外。与血管对齐的耳神经从基底区延伸到周围区,并越过淋巴管,从而形成神经,血管,和淋巴网络。
■由于这些是耳廓皮肤的重要组织成分,这个结果表明耳神经纤维,并且血液和淋巴管可以相互协调以直接响应耳廓刺激。