PDF(Pubmed)
Abstract：
BACKGROUND: Bronchial asthma is closely related to the occurrence of attention-deficit hyperactivity disorder (ADHD) in children, which can easily have adverse effects on children\'s learning and social interactions. Studies have shown that childhood asthma can increase the risk of ADHD and the core symptoms of ADHD. Compared with children with ADHD alone, children with asthma and ADHD are more likely to show high levels of hyperactivity, hyperactive-impulsive and other externalizing behaviors and anxiety in clinical practice and have more symptoms of somatization and emotional internalization.
OBJECTIVE: To explore the relationship between ADHD in children and bronchial asthma and to analyze its influencing factors.
METHODS: This retrospective cohort study was conducted at Dongying People\'s Hospital from September 2018 to August 2023. Children diagnosed with ADHD at this hospital were selected as the ADHD group, while healthy children without ADHD who underwent physical examinations during the same period served as the control group. Clinical and parental data were collected for all participating children, and multivariate logistic regression analysis was employed to identify risk factors for comorbid asthma in children with ADHD.
RESULTS: Significant differences were detected between the ADHD group and the control group in terms of family history of asthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergy medications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationship status (P < 0.05). Out of the 183 children in the ADHD group, 25 had comorbid asthma, resulting in a comorbidity rate of 13.66% (25/183), compared to the comorbidity rate of 2.91% (16/549) among the 549 children in the control group. The difference in the asthma comorbidity rate between the two groups was statistically significant (P < 0.05). The results of the multivariate logistic regression analysis indicated that family history of asthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergy medications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationship status are independent risk factors increasing the risk of comorbid asthma in children with ADHD (P < 0.05).
CONCLUSIONS: Children with ADHD were more likely to have comorbid asthma than healthy control children were. A family history of asthma, adverse maternal factors during pregnancy, and parental relationship status were identified as risk factors influencing the comorbidity of asthma in children with ADHD. Clinically, targeted interventions based on these factors can be implemented to reduce the risk of comorbid asthma. This information is relevant for results sections of abstracts in scientific articles.
OBJECTIVE: To explore the relationship between ADHD in children and bronchial asthma and to analyze its influencing factors.
METHODS: This retrospective cohort study was conducted at Dongying People\'s Hospital from September 2018 to August 2023. Children diagnosed with ADHD at this hospital were selected as the ADHD group, while healthy children without ADHD who underwent physical examinations during the same period served as the control group. Clinical and parental data were collected for all participating children, and multivariate logistic regression analysis was employed to identify risk factors for comorbid asthma in children with ADHD.
RESULTS: Significant differences were detected between the ADHD group and the control group in terms of family history of asthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergy medications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationship status (P < 0.05). Out of the 183 children in the ADHD group, 25 had comorbid asthma, resulting in a comorbidity rate of 13.66% (25/183), compared to the comorbidity rate of 2.91% (16/549) among the 549 children in the control group. The difference in the asthma comorbidity rate between the two groups was statistically significant (P < 0.05). The results of the multivariate logistic regression analysis indicated that family history of asthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergy medications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationship status are independent risk factors increasing the risk of comorbid asthma in children with ADHD (P < 0.05).
CONCLUSIONS: Children with ADHD were more likely to have comorbid asthma than healthy control children were. A family history of asthma, adverse maternal factors during pregnancy, and parental relationship status were identified as risk factors influencing the comorbidity of asthma in children with ADHD. Clinically, targeted interventions based on these factors can be implemented to reduce the risk of comorbid asthma. This information is relevant for results sections of abstracts in scientific articles.
摘要：
背景：支气管哮喘与儿童注意缺陷多动障碍（ADHD）的发生密切相关，这很容易对儿童的学习和社会交往产生不利影响。研究表明，儿童哮喘可以增加ADHD的风险和ADHD的核心症状。与单独患有多动症的儿童相比，患有哮喘和多动症的儿童更有可能表现出高水平的多动症，在临床实践中，过度活跃-冲动和其他外化行为和焦虑，并有更多的躯体化和情绪内化症状。
目的：探讨儿童多动症与支气管哮喘的关系及其影响因素。
方法：本回顾性队列研究于2018年9月至2023年8月在东营市人民医院进行。选择在该医院诊断为ADHD的儿童作为ADHD组。而同期接受体检的无ADHD健康儿童作为对照组。收集了所有参与儿童的临床和父母数据，采用多因素logistic回归分析确定ADHD患儿并发哮喘的危险因素.
结果：在哮喘家族史和过敏性疾病方面，ADHD组与对照组之间存在显着差异，怀孕期间的产妇并发症，母亲在怀孕期间使用哮喘和过敏药物，孕妇在怀孕期间的焦虑和抑郁，亲子关系状况(P<0.05)。在多动症组的183名儿童中，25人患有哮喘，共病率为13.66%(25/183)，对照组549名儿童的合并症发生率为2.91%(16/549)。两组哮喘合并症发生率比较差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,哮喘家族史和过敏性疾病,怀孕期间的产妇并发症，母亲在怀孕期间使用哮喘和过敏药物，孕妇在怀孕期间的焦虑和抑郁，父母关系状况是增加ADHD患儿合并哮喘风险的独立危险因素(P<0.05)。
结论：患有ADHD的儿童比健康对照儿童更容易患哮喘。哮喘家族史,孕期不良孕产因素,和父母关系状况被确定为影响ADHD患儿哮喘共病的危险因素。临床上,基于这些因素的有针对性的干预措施可以降低哮喘共病的风险.此信息与科学文章摘要的结果部分相关。
目的：探讨儿童多动症与支气管哮喘的关系及其影响因素。
方法：本回顾性队列研究于2018年9月至2023年8月在东营市人民医院进行。选择在该医院诊断为ADHD的儿童作为ADHD组。而同期接受体检的无ADHD健康儿童作为对照组。收集了所有参与儿童的临床和父母数据，采用多因素logistic回归分析确定ADHD患儿并发哮喘的危险因素.
结果：在哮喘家族史和过敏性疾病方面，ADHD组与对照组之间存在显着差异，怀孕期间的产妇并发症，母亲在怀孕期间使用哮喘和过敏药物，孕妇在怀孕期间的焦虑和抑郁，亲子关系状况(P<0.05)。在多动症组的183名儿童中，25人患有哮喘，共病率为13.66%(25/183)，对照组549名儿童的合并症发生率为2.91%(16/549)。两组哮喘合并症发生率比较差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,哮喘家族史和过敏性疾病,怀孕期间的产妇并发症，母亲在怀孕期间使用哮喘和过敏药物，孕妇在怀孕期间的焦虑和抑郁，父母关系状况是增加ADHD患儿合并哮喘风险的独立危险因素(P<0.05)。
结论：患有ADHD的儿童比健康对照儿童更容易患哮喘。哮喘家族史,孕期不良孕产因素,和父母关系状况被确定为影响ADHD患儿哮喘共病的危险因素。临床上,基于这些因素的有针对性的干预措施可以降低哮喘共病的风险.此信息与科学文章摘要的结果部分相关。
