Abstract：
BACKGROUND: During pregnancy, the woman\'s body undergoes anatomical and physiological changes, making this period susceptible to maternal-fetal diseases and complications. The consequences of not treating pregnant women include premature birth, low birth weight fetuses, and postnatal behavior disorders. Developing new therapies can accelerate the discovery of safe and effective drugs, contributing to designing novel natural and synthetic products to treat complications the pregnancy.
OBJECTIVE: This study aimed to carry out a patent review to identify and explore trends in innovation and therapeutic strategies for treating pregnant women.
METHODS: The Espacenet and WIPO databases were used, with the inclusion criteria being the keywords \"pregnancy and drug\" and code A61k, from 2008 to 2023, and as exclusion were the access to the patent and focus on human pregnant women.
RESULTS: After the final screening, 32 patents were selected, with strategies for the treatment of diseases in pregnant women. Of these, 20 patents are on preclinical studies on animals and 12 on pregnant women. It was observed that universities lead the ranking of applications (17/32), and China has the highest number of patents (18/32). Most findings contain herbal medicines and/or the association of natural extracts with synthetic drugs.
CONCLUSIONS: From this perspective, new drug administration systems were also developed, which can be a promising source for obtaining new medicines for the treatment of pregnant women; however, research is still limited and shows a gap in stimulating the rapid development of safe drugs that improve the health of pregnant women.
OBJECTIVE: This study aimed to carry out a patent review to identify and explore trends in innovation and therapeutic strategies for treating pregnant women.
METHODS: The Espacenet and WIPO databases were used, with the inclusion criteria being the keywords \"pregnancy and drug\" and code A61k, from 2008 to 2023, and as exclusion were the access to the patent and focus on human pregnant women.
RESULTS: After the final screening, 32 patents were selected, with strategies for the treatment of diseases in pregnant women. Of these, 20 patents are on preclinical studies on animals and 12 on pregnant women. It was observed that universities lead the ranking of applications (17/32), and China has the highest number of patents (18/32). Most findings contain herbal medicines and/or the association of natural extracts with synthetic drugs.
CONCLUSIONS: From this perspective, new drug administration systems were also developed, which can be a promising source for obtaining new medicines for the treatment of pregnant women; however, research is still limited and shows a gap in stimulating the rapid development of safe drugs that improve the health of pregnant women.
摘要：
背景：在怀孕期间，女人的身体经历解剖和生理变化，使这一时期容易发生母胎疾病和并发症。不治疗孕妇的后果包括早产，低出生体重胎儿,和产后行为障碍。开发新的疗法可以加速发现安全有效的药物,有助于设计新颖的天然和合成产品来治疗妊娠并发症。
目的：本研究旨在进行专利综述，以确定和探索治疗孕妇的创新和治疗策略的趋势。
方法：使用Espacenet和WIPO数据库，纳入标准是关键词“怀孕和药物”和代码A61k，从2008年到2023年，被排除在外的是获得专利和关注人类孕妇。
结果：在最终筛查后，32项专利入选,治疗孕妇疾病的策略。其中,20项专利是关于动物的临床前研究，12项关于孕妇。据观察，大学在申请排名中领先(17/32)，中国拥有最多的专利（18/32）。大多数发现包含草药和/或天然提取物与合成药物的关联。
结论：从这个角度来看，还开发了新的药物管理系统，这可能是获得治疗孕妇的新药的有希望的来源；然而，研究仍然有限，并且显示在刺激改善孕妇健康的安全药物的快速开发方面存在差距。
目的：本研究旨在进行专利综述，以确定和探索治疗孕妇的创新和治疗策略的趋势。
方法：使用Espacenet和WIPO数据库，纳入标准是关键词“怀孕和药物”和代码A61k，从2008年到2023年，被排除在外的是获得专利和关注人类孕妇。
结果：在最终筛查后，32项专利入选,治疗孕妇疾病的策略。其中,20项专利是关于动物的临床前研究，12项关于孕妇。据观察，大学在申请排名中领先(17/32)，中国拥有最多的专利（18/32）。大多数发现包含草药和/或天然提取物与合成药物的关联。
结论：从这个角度来看，还开发了新的药物管理系统，这可能是获得治疗孕妇的新药的有希望的来源；然而，研究仍然有限，并且显示在刺激改善孕妇健康的安全药物的快速开发方面存在差距。
