PDF(Pubmed)
Abstract：
BACKGROUND: To investigate the impact of wearing spectacle lenses with highly aspherical lenslets (HAL) for 3 years and the impact of switching from single-vision lenses (SVL) to HAL on choroidal thickness (ChT).
METHODS: Fifty-one participants who had already worn HAL for 2 years continued wearing them for an additional year (HAL group). Further, 50 and 41 participants who had worn spectacle lenses with slightly aspherical lenslets (SAL) and SVL for 2 years, respectively, switched to wearing HAL for another year (SAL-HAL and SVL-HAL groups). Additionally, 48 new participants aged 10-15 years were enrolled to wear SVL at the third year (new-SVL group). ChT was measured every 6 months throughout the study.
RESULTS: Significant differences were observed in the changes in ChT among the four groups at the third year (all P < 0.05 except for the outer nasal region: P = 0.09), with the new-SVL group showing larger reductions compared with the other three groups. However, none of the three HAL-wearing groups showed significant changes in ChT at the third year (all P > 0.05). When comparing the changes in ChT for 3 years among the HAL, SAL-HAL, and SVL-HAL groups, significant differences were found before switching to HAL, but these differences were abolished after all participants switched to HAL.
CONCLUSIONS: Compared to those in the SVL group, choroid thinning was significantly inhibited in all the HAL groups. Wearing HAL for 3 years no longer had a choroidal thickening effect but could still inhibit choroidal thinning compared to wearing SVL.
BACKGROUND: The study was registered at the Chinese Clinical Trial Registry (ChiCTR1800017683), http://www.chictr.org.cn/showproj.aspx?proj=29789 .
METHODS: Fifty-one participants who had already worn HAL for 2 years continued wearing them for an additional year (HAL group). Further, 50 and 41 participants who had worn spectacle lenses with slightly aspherical lenslets (SAL) and SVL for 2 years, respectively, switched to wearing HAL for another year (SAL-HAL and SVL-HAL groups). Additionally, 48 new participants aged 10-15 years were enrolled to wear SVL at the third year (new-SVL group). ChT was measured every 6 months throughout the study.
RESULTS: Significant differences were observed in the changes in ChT among the four groups at the third year (all P < 0.05 except for the outer nasal region: P = 0.09), with the new-SVL group showing larger reductions compared with the other three groups. However, none of the three HAL-wearing groups showed significant changes in ChT at the third year (all P > 0.05). When comparing the changes in ChT for 3 years among the HAL, SAL-HAL, and SVL-HAL groups, significant differences were found before switching to HAL, but these differences were abolished after all participants switched to HAL.
CONCLUSIONS: Compared to those in the SVL group, choroid thinning was significantly inhibited in all the HAL groups. Wearing HAL for 3 years no longer had a choroidal thickening effect but could still inhibit choroidal thinning compared to wearing SVL.
BACKGROUND: The study was registered at the Chinese Clinical Trial Registry (ChiCTR1800017683), http://www.chictr.org.cn/showproj.aspx?proj=29789 .
摘要：
背景：研究佩戴具有高度非球面透镜（HAL）的眼镜镜片3年的影响以及从单视镜片（SVL）切换到HAL对脉络膜厚度（ChT）的影响。
方法：51名已经佩戴HAL2年的参与者继续再佩戴1年（HAL组）。Further,50名和41名参与者佩戴了微非球面透镜（SAL）和SVL的眼镜镜片2年，分别,改戴HAL一年（SAL-HAL和SVL-HAL组）。此外,48名年龄在10-15岁的新参与者在第三年参加了SVL（新SVL组）。在整个研究中每6个月测量ChT。
结果：第三年四组之间的ChT变化存在显着差异（除外鼻区外，所有P<0.05：P=0.09），与其他三组相比，新SVL组显示出更大的减少。然而,三个HAL佩戴组均未出现第3年ChT显著变化(均P>0.05)。当比较HAL之间3年的ChT变化时，萨尔-哈尔,和SVL-HAL组，在转换为HAL之前发现了显着差异，但是在所有参与者改用HAL后，这些差异被消除了。
结论：与SVL组相比，在所有HAL组中，脉络膜变薄均受到显着抑制。与佩戴SVL相比，佩戴HAL3年不再具有脉络膜增厚作用，但仍然可以抑制脉络膜变薄。
背景：该研究已在中国临床试验注册中心（ChiCTR1800017683）注册，http://www。chictr.org.cn/showproj.aspx?proj=29789。
方法：51名已经佩戴HAL2年的参与者继续再佩戴1年（HAL组）。Further,50名和41名参与者佩戴了微非球面透镜（SAL）和SVL的眼镜镜片2年，分别,改戴HAL一年（SAL-HAL和SVL-HAL组）。此外,48名年龄在10-15岁的新参与者在第三年参加了SVL（新SVL组）。在整个研究中每6个月测量ChT。
结果：第三年四组之间的ChT变化存在显着差异（除外鼻区外，所有P<0.05：P=0.09），与其他三组相比，新SVL组显示出更大的减少。然而,三个HAL佩戴组均未出现第3年ChT显著变化(均P>0.05)。当比较HAL之间3年的ChT变化时，萨尔-哈尔,和SVL-HAL组，在转换为HAL之前发现了显着差异，但是在所有参与者改用HAL后，这些差异被消除了。
结论：与SVL组相比，在所有HAL组中，脉络膜变薄均受到显着抑制。与佩戴SVL相比，佩戴HAL3年不再具有脉络膜增厚作用，但仍然可以抑制脉络膜变薄。
背景：该研究已在中国临床试验注册中心（ChiCTR1800017683）注册，http://www。chictr.org.cn/showproj.aspx?proj=29789。
