铂诱导的 ITGA6 上调促进卵巢癌化疗耐药和扩散。
关键词: Integrin Metastasis Ovarian Cancer chemoresistance
Mesh : Humans Integrin alpha6 / metabolism genetics Female Drug Resistance, Neoplasm / genetics drug effects Ovarian Neoplasms / drug therapy genetics pathology metabolism Up-Regulation / drug effects Animals Cell Line, Tumor Platinum / pharmacology therapeutic use Carcinoma, Ovarian Epithelial / drug therapy genetics metabolism pathology Antineoplastic Agents / pharmacology therapeutic use Gene Expression Regulation, Neoplastic / drug effects
来 源:
DOI:10.1038/s44321-024-00069-3
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