关键词: Intracranial schwannomatosis Retrosigmoid approach Trigeminal schwannoma Vestibular schwannoma

Mesh : Humans Female Adult Cranial Nerve Neoplasms / surgery diagnostic imaging pathology Neurilemmoma / surgery diagnostic imaging pathology Neuroma, Acoustic / surgery diagnostic imaging pathology Trigeminal Nerve Diseases / surgery pathology Trigeminal Nerve / surgery pathology Neurosurgical Procedures / methods Vestibular Nerve / surgery pathology Magnetic Resonance Imaging

来  源:   DOI:10.1016/j.wneu.2024.04.101

Abstract:
BACKGROUND: A schwannoma is a nerve sheath tumor that is formed by Schwann cells. Vestibular schwannomas are thought to account for the majority of intracranial schwannomas. Nonvestibular schwannomas account for about 10%, about half of which are trigeminal schwannomas. Multiple intracranial schwannomas originating from different cranial nerves are extremely rare.
METHODS: We describe the clinical case of a 42-year-old female patient with vestibular schwannoma and multiple trigeminal schwannomas.
RESULTS: That case shows how multiple trigeminal schwannomas were identified intraoperatively during elective surgery for vestibular schwannoma removal, most of which were resected. No new neurological deficits were observed in the patient.
CONCLUSIONS: The presence of multiple intracranial schwannomas is extremely rare in neurosurgical practice and can change the intraoperative strategy and the course of the surgery.
摘要:
背景:神经鞘瘤是由雪旺细胞形成的神经鞘瘤。前庭神经鞘瘤被认为占颅内神经鞘瘤的大多数。非前庭神经鞘瘤约占10%,其中大约一半是三叉神经鞘瘤。起源于不同颅神经的多发性颅内神经鞘瘤极为罕见。
我们描述了一名42岁女性前庭神经鞘瘤和多发性三叉神经鞘瘤患者的临床病例。该病例显示了在切除前庭神经鞘瘤的择期手术中如何在术中识别出多个三叉神经鞘瘤,其中大部分被切除。在患者中未观察到新的神经功能缺损。
结论:多发性颅内神经鞘瘤的存在在神经外科实践中极为罕见,可以改变术中策略和手术过程。
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