Mesh : Humans Male Esophageal Stenosis / etiology drug therapy Actinomycosis / drug therapy diagnosis complications Child, Preschool Amoxicillin / therapeutic use administration & dosage Anti-Bacterial Agents / therapeutic use administration & dosage Penicillin G / therapeutic use administration & dosage

来  源:   DOI:10.1542/peds.2023-062823

Abstract:
Esophageal stenosis can cause vomiting or dysphagia in children and is commonly treated with esophageal balloon dilation. However, surgery may be required if the stenosis does not respond to dilation. Although esophageal actinomycosis can cause severe esophageal strictures and be refractory to balloon dilation, it has been reported to respond effectively to antimicrobial therapy in adults. However, the course of the disease and appropriate treatment strategies in children are not well understood. We present a case of a previously healthy 2-year-old boy diagnosed with esophageal stenosis because of actinomycosis. The patient was treated with intravenous penicillin G, followed by oral amoxicillin for 8 weeks and 6 months, respectively. After completion of the antimicrobial treatment, the patient showed improvement in symptoms and endoscopic findings. At the 1-year follow-up, the patient showed consistent weight gain and normal growth without further intervention. This case highlights the importance of considering esophageal actinomycosis as a potential cause of esophageal stenosis in children and the potential effectiveness of antimicrobial therapy in avoiding surgical intervention.
摘要:
食管狭窄可引起儿童呕吐或吞咽困难,通常采用食管球囊扩张术治疗。然而,如果狭窄对扩张没有反应,则可能需要手术。尽管食管放线菌病会导致严重的食管狭窄,并且球囊扩张难以治愈,据报道,它对成人抗菌治疗有有效反应。然而,儿童的病程和适当的治疗策略尚不清楚.我们介绍了一例先前健康的2岁男孩,该男孩因放线菌病被诊断为食管狭窄。患者接受静脉注射青霉素G治疗,随后口服阿莫西林8周和6个月,分别。抗菌治疗结束后,患者的症状和内镜检查结果有所改善.在1年的随访中,患者表现出持续的体重增加和正常生长,没有进一步干预。该病例强调了将食管放线菌病视为儿童食管狭窄的潜在原因的重要性,以及抗菌治疗在避免手术干预方面的潜在有效性。
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