PDF(Pubmed)
Abstract：
UNASSIGNED: We investigated cognitive profiles among diverse, middle-aged and older Hispanic/Latino adults in the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) cohort using a cross-sectional observational study design.
UNASSIGNED: Based on weighted descriptive statistics, the average baseline age of the target population was 56.4 years, slightly more than half were women (54.6%), and 38.4% reported less than a high school education. We used latent profile analysis of demographically adjusted z scores on SOL-INCA neurocognitive tests spanning domains of verbal memory, language, processing speed, and executive function.
UNASSIGNED: Statistical fit assessment indices combined with clinical interpretation suggested five profiles: (1) a Higher Global group performing in the average-to-high-average range across all cognitive and instrumental activity of daily living (IADL) tests (13.8%); (2) a Higher Memory group with relatively high performance on memory tests but average performance across all other cognitive/IADL tests (24.6%); (3) a Lower Memory group with relatively low performance on memory tests but average performance across all other cognitive/IADL tests (32.8%); (4) a Lower Executive Function group with relatively low performance on executive function and processing speed tests but average-to-low-average performance across all other cognitive/IADL tests (16.6%); and (5) a Lower Global group performing low-average-to-mildly impaired across all cognitive/IADL tests (12.1%).
UNASSIGNED: Our results provide evidence of heterogeneity in the cognitive profiles of a representative, community-dwelling sample of diverse Hispanic/Latino adults. Our analyses yielded cognitive profiles that may assist efforts to better understand the early cognitive changes that may portend Alzheimer\'s disease and related dementias among diverse Hispanics/Latinos.
UNASSIGNED: The present study characterized cognitive profiles among diverse middle-aged and older Hispanic/Latino adults.Latent profile analysis of neurocognitive test scores was the primary analysis conducted.The target population consists of middle-aged and older Hispanic/Latino adults enrolled in the Hispanic Community Health Study/Study of Latinos and ancillary Study of Latinos - Investigation of Neurocognitive Aging.
UNASSIGNED: Based on weighted descriptive statistics, the average baseline age of the target population was 56.4 years, slightly more than half were women (54.6%), and 38.4% reported less than a high school education. We used latent profile analysis of demographically adjusted z scores on SOL-INCA neurocognitive tests spanning domains of verbal memory, language, processing speed, and executive function.
UNASSIGNED: Statistical fit assessment indices combined with clinical interpretation suggested five profiles: (1) a Higher Global group performing in the average-to-high-average range across all cognitive and instrumental activity of daily living (IADL) tests (13.8%); (2) a Higher Memory group with relatively high performance on memory tests but average performance across all other cognitive/IADL tests (24.6%); (3) a Lower Memory group with relatively low performance on memory tests but average performance across all other cognitive/IADL tests (32.8%); (4) a Lower Executive Function group with relatively low performance on executive function and processing speed tests but average-to-low-average performance across all other cognitive/IADL tests (16.6%); and (5) a Lower Global group performing low-average-to-mildly impaired across all cognitive/IADL tests (12.1%).
UNASSIGNED: Our results provide evidence of heterogeneity in the cognitive profiles of a representative, community-dwelling sample of diverse Hispanic/Latino adults. Our analyses yielded cognitive profiles that may assist efforts to better understand the early cognitive changes that may portend Alzheimer\'s disease and related dementias among diverse Hispanics/Latinos.
UNASSIGNED: The present study characterized cognitive profiles among diverse middle-aged and older Hispanic/Latino adults.Latent profile analysis of neurocognitive test scores was the primary analysis conducted.The target population consists of middle-aged and older Hispanic/Latino adults enrolled in the Hispanic Community Health Study/Study of Latinos and ancillary Study of Latinos - Investigation of Neurocognitive Aging.
摘要：
■我们调查了不同的认知特征，拉丁裔研究中的中老年西班牙裔/拉丁裔成年人-使用横断面观察性研究设计的神经认知老化调查（SOL-INCA）队列。
■基于加权描述性统计，目标人群的平均基线年龄为56.4岁，略多于一半是女性(54.6%)，38.4%的人报告低于高中学历。我们在跨越言语记忆领域的SOL-INCA神经认知测试中使用了人口统计学调整的z分数的潜在谱分析，语言,处理速度,和执行功能。
■统计拟合评估指数结合临床解释提出了五个概况：（1）在所有认知和日常工具活动（IADL）测试中，全球较高的组表现在平均到高平均范围内（13.8％）；（2）在记忆测试中表现相对较高，但在所有其他认知/IADL测试中表现平均表现较低，但在所有ADL测试中表现较低的
■我们的结果提供了代表认知特征异质性的证据，不同西班牙裔/拉丁裔成年人的社区居住样本。我们的分析得出的认知概况可能有助于更好地理解早期认知变化，这些变化可能预示着不同的西班牙裔/拉丁美洲人中的阿尔茨海默病和相关痴呆症。
■本研究描述了不同的中年和老年西班牙裔/拉丁裔成年人的认知特征。神经认知测试成绩的潜在概况分析是进行的主要分析。目标人群包括参加西班牙裔社区健康研究/拉丁裔研究和拉丁裔辅助研究的中年和老年西班牙裔/拉丁裔成年人-神经认知衰老调查。
■基于加权描述性统计，目标人群的平均基线年龄为56.4岁，略多于一半是女性(54.6%)，38.4%的人报告低于高中学历。我们在跨越言语记忆领域的SOL-INCA神经认知测试中使用了人口统计学调整的z分数的潜在谱分析，语言,处理速度,和执行功能。
■统计拟合评估指数结合临床解释提出了五个概况：（1）在所有认知和日常工具活动（IADL）测试中，全球较高的组表现在平均到高平均范围内（13.8％）；（2）在记忆测试中表现相对较高，但在所有其他认知/IADL测试中表现平均表现较低，但在所有ADL测试中表现较低的
■我们的结果提供了代表认知特征异质性的证据，不同西班牙裔/拉丁裔成年人的社区居住样本。我们的分析得出的认知概况可能有助于更好地理解早期认知变化，这些变化可能预示着不同的西班牙裔/拉丁美洲人中的阿尔茨海默病和相关痴呆症。
■本研究描述了不同的中年和老年西班牙裔/拉丁裔成年人的认知特征。神经认知测试成绩的潜在概况分析是进行的主要分析。目标人群包括参加西班牙裔社区健康研究/拉丁裔研究和拉丁裔辅助研究的中年和老年西班牙裔/拉丁裔成年人-神经认知衰老调查。
