关键词: Melan-A T1W hyperintensity case report cervical vertebra melanocytic neoplasia melanoma of unknown primary melanotic schwannoma

来  源:   DOI:10.3389/fvets.2024.1334813   PDF(Pubmed)

Abstract:
A 7-year-old Lhasa Apso presented with a history of left thoracic limb lameness and neck pain. Magnetic resonance imaging revealed a well-defined, extradural lesion that was hyperintense on T1-weighted (T1W) images and isointense on T2-weighted (T2W) images and T2* images located at the left lamina of the C4 vertebra. Computed tomography showed an isoattenuating and contrast-enhancing mass centered on the left C4 vertebral lamina with associated osteolysis. The mass was surgically debulked, and histopathology revealed a malignant melanocytic tumour. The patient recovered completely and received radiotherapy and three doses of the melanoma vaccine as adjunctive treatment. Eighteen months following treatment, the patient presented with neck pain again, but further investigations were declined at this stage, and the patient was euthanised. To the author\'s knowledge, this is the first case report describing the imaging characteristics of a cervical extradural melanocytic tumour in a dog. This case illustrates the MRI and CT imaging features and treatment of a canine melanocytic tumour of the cervical vertebrae.
摘要:
7岁的拉萨Apso有左胸肢跛行和颈部疼痛的病史。磁共振成像显示,硬膜外病变在T1加权(T1W)图像上为高强度,在位于C4椎骨左椎板的T2加权(T2W)图像和T2*图像上为等强度。计算机断层扫描显示,以左侧C4椎板为中心的等衰减和对比增强肿块,并伴有骨质溶解。手术切除了肿块,组织病理学显示为恶性黑素细胞肿瘤。患者完全康复,并接受放射治疗和三剂黑色素瘤疫苗作为辅助治疗。治疗18个月后,患者再次出现颈部疼痛,但是在这个阶段进一步的调查被拒绝了,病人被安乐死了.据作者所知,这是第一例描述狗宫颈硬膜外黑素细胞肿瘤的影像学特征的病例报告。此病例说明了颈椎犬黑素细胞肿瘤的MRI和CT成像特征和治疗。
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