PDF(Pubmed)
Abstract：
Deep anterior lamellar keratoplasty (DALK) involves the selective replacement of diseased corneal stroma while preserving healthy unaffected endothelium. While DALK has failed to gain widespread popularity, improved visual and refractive outcomes of large-diameter grafts, which patients directly perceive following suture removal, may represent a compelling reason to shift toward DALK. Since the unaffected host endothelium is retained, DALK offers the opportunity to use large-diameter grafts, which reliably achieves maximum visual potential without an increased risk of immune-mediated stromal rejection. In this narrative review, we evaluate the current evidence on large-diameter DALK including surgical technique and clinical outcomes.
摘要：
深前板层角膜移植术（DALK）涉及选择性置换患病的角膜基质，同时保留健康的未受影响的内皮。虽然DALK未能获得广泛的普及，改善大直径移植物的视觉和屈光结果，患者在缝合后直接感知到，可能是转向DALK的令人信服的理由。由于未受影响的宿主内皮被保留，DALK提供了使用大直径移植物的机会，它可靠地实现了最大的视觉潜力，而不会增加免疫介导的基质排斥的风险。在这篇叙述性评论中，我们评估了大直径DALK的现有证据,包括手术技术和临床结果.
