PDF(Pubmed)
Abstract：
BACKGROUND: Sarcoidosis is a multisystemic disease characterized by granulomatous inflammation. Sarcoidosis often poses a diagnostic challenge owing to its nonspecific or mild clinical features. In 20-35% of cases, sarcoidosis initially presents on skin. However, skin lesions commonly mimic dermatological conditions. Therefore, it is important to not underestimate the skin manifestations and perform histopathological examinations to make a timely diagnosis.
METHODS: We present two cases of 33-year-old Caucasian female patients with orange-red macules and plaques that developed in the eyebrow area 1 and 6 years after microblading, respectively. Histopathological examination confirmed a diagnosis of sarcoidosis. The lymph nodes and lungs were also affected in both patients.
CONCLUSIONS: Our two reports suggest that an esthetic procedure involving dermal or subcutaneous injection of foreign materials can trigger the development of cutaneous and systemic sarcoidosis. However, this relationship has not been described yet. Physicians should, therefore, be aware of this complication to properly evaluate and treat such patients in a timely manner.
METHODS: We present two cases of 33-year-old Caucasian female patients with orange-red macules and plaques that developed in the eyebrow area 1 and 6 years after microblading, respectively. Histopathological examination confirmed a diagnosis of sarcoidosis. The lymph nodes and lungs were also affected in both patients.
CONCLUSIONS: Our two reports suggest that an esthetic procedure involving dermal or subcutaneous injection of foreign materials can trigger the development of cutaneous and systemic sarcoidosis. However, this relationship has not been described yet. Physicians should, therefore, be aware of this complication to properly evaluate and treat such patients in a timely manner.
摘要：
背景：结节病是一种以肉芽肿性炎症为特征的多系统疾病。结节病通常由于其非特异性或轻度的临床特征而构成诊断挑战。在20-35%的病例中，结节病最初出现在皮肤上。然而,皮肤损伤通常模拟皮肤病。因此,重要的是不要低估皮肤表现并进行组织病理学检查以及时诊断。
方法：我们介绍了两例33岁的白种人女性患者，在微裂后1年和6年在眉毛区域出现橙红色斑斑和斑块，分别。组织病理学检查证实结节病的诊断。两名患者的淋巴结和肺也受到影响。
结论：我们的两份报告表明，涉及皮肤或皮下注射异物的美学程序可引发皮肤和全身结节病的发展。然而,这种关系还没有描述。医生应该，因此,意识到这种并发症，以便及时评估和治疗此类患者。
方法：我们介绍了两例33岁的白种人女性患者，在微裂后1年和6年在眉毛区域出现橙红色斑斑和斑块，分别。组织病理学检查证实结节病的诊断。两名患者的淋巴结和肺也受到影响。
结论：我们的两份报告表明，涉及皮肤或皮下注射异物的美学程序可引发皮肤和全身结节病的发展。然而,这种关系还没有描述。医生应该，因此,意识到这种并发症，以便及时评估和治疗此类患者。
