PDF(Pubmed)
Abstract：
UNASSIGNED: Individuals with amblyopia experience central vision deficits, including loss of visual acuity, binocular vision, and stereopsis. In this study, we examine the differences in peripheral binocular imbalance in children with anisometropic amblyopia, strabismic amblyopia, and typical binocular vision to determine if there are systematic patterns of deficits across the visual field.
UNASSIGNED: This prospective cohort study recruited 12 participants with anisometropic amblyopia, 10 with strabismic amblyopia, and 10 typically sighted controls (age range, 5-18 years). Binocular imbalance was tested at 0°, 4°, and 8° eccentricities (4 angular locations each) using band-pass filtered Auckland optotypes (5 cycles per optotype) dichoptically presented with differing contrast to each eye. The interocular contrast ratio was adjusted until the participant reported each optotype with equal frequency.
UNASSIGNED: Participants with anisometropic and strabismic amblyopia had a more balanced contrast ratio, or decreased binocular imbalance, at 4° and 8° eccentricities as compared with central vision. Participants with strabismic amblyopia had significantly more binocular imbalance in the periphery as compared with individuals with anisometropic amblyopia or controls. A linear mixed effects model showed a main effect for strabismic amblyopia and eccentricity on binocular imbalance across the visual field.
UNASSIGNED: There is evidence of decreased binocularity deficits, or interocular suppression, in the periphery in anisometropic and strabismic amblyopia as compared with controls. Notably, those with strabismic amblyopia exhibited more significant peripheral binocular imbalance. These variations in binocularity across the visual field among different amblyopia subtypes may necessitate tailored approaches for dichoptic treatment.
UNASSIGNED: This prospective cohort study recruited 12 participants with anisometropic amblyopia, 10 with strabismic amblyopia, and 10 typically sighted controls (age range, 5-18 years). Binocular imbalance was tested at 0°, 4°, and 8° eccentricities (4 angular locations each) using band-pass filtered Auckland optotypes (5 cycles per optotype) dichoptically presented with differing contrast to each eye. The interocular contrast ratio was adjusted until the participant reported each optotype with equal frequency.
UNASSIGNED: Participants with anisometropic and strabismic amblyopia had a more balanced contrast ratio, or decreased binocular imbalance, at 4° and 8° eccentricities as compared with central vision. Participants with strabismic amblyopia had significantly more binocular imbalance in the periphery as compared with individuals with anisometropic amblyopia or controls. A linear mixed effects model showed a main effect for strabismic amblyopia and eccentricity on binocular imbalance across the visual field.
UNASSIGNED: There is evidence of decreased binocularity deficits, or interocular suppression, in the periphery in anisometropic and strabismic amblyopia as compared with controls. Notably, those with strabismic amblyopia exhibited more significant peripheral binocular imbalance. These variations in binocularity across the visual field among different amblyopia subtypes may necessitate tailored approaches for dichoptic treatment.
摘要：
■弱视患者会出现中央视觉缺陷，包括视力丧失,双目视觉,和立体视觉。在这项研究中,我们研究了屈光参差性弱视儿童周围双眼失衡的差异，斜视弱视,和典型的双目视觉，以确定是否存在整个视野中的系统缺陷模式。
■这项前瞻性队列研究招募了12名患有屈光参差性弱视的参与者，10例斜视性弱视，和10个典型的视力控制(年龄范围，5-18岁）。在0°测试双眼失衡，4°,和使用带通滤波的奥克兰视模（每个视模5个周期）的8°偏心率（每个角度位置4个），对每只眼睛的对比度不同。调整眼间对比度，直到参与者以相等的频率报告每个验光类型。
■屈光参差和斜视性弱视的参与者的对比度更平衡，或减少双眼失衡，与中央视觉相比，在4°和8°偏心率下。与屈光参差性弱视患者或对照组相比，斜视性弱视患者的周边双眼失衡明显更多。线性混合效应模型显示了斜视性弱视和偏心率对整个视野中双眼失衡的主要影响。
■有证据表明双眼缺陷减少，或眼间抑制，与对照组相比，在屈光参差和斜视性弱视的外围。值得注意的是,斜视弱视者表现出更明显的外周双眼失衡。不同弱视亚型之间在整个视野中的双眼性的这些变化可能需要量身定制的双目治疗方法。
■这项前瞻性队列研究招募了12名患有屈光参差性弱视的参与者，10例斜视性弱视，和10个典型的视力控制(年龄范围，5-18岁）。在0°测试双眼失衡，4°,和使用带通滤波的奥克兰视模（每个视模5个周期）的8°偏心率（每个角度位置4个），对每只眼睛的对比度不同。调整眼间对比度，直到参与者以相等的频率报告每个验光类型。
■屈光参差和斜视性弱视的参与者的对比度更平衡，或减少双眼失衡，与中央视觉相比，在4°和8°偏心率下。与屈光参差性弱视患者或对照组相比，斜视性弱视患者的周边双眼失衡明显更多。线性混合效应模型显示了斜视性弱视和偏心率对整个视野中双眼失衡的主要影响。
■有证据表明双眼缺陷减少，或眼间抑制，与对照组相比，在屈光参差和斜视性弱视的外围。值得注意的是,斜视弱视者表现出更明显的外周双眼失衡。不同弱视亚型之间在整个视野中的双眼性的这些变化可能需要量身定制的双目治疗方法。
