PDF(Pubmed)
Abstract：
UNASSIGNED: Neuroglial heterotopia is a rare lesion composed of differentiated neuroectodermal cells that manifest in extracranial locations, with the majority of cases predominantly occurring in the head and neck region. Retroperitoneal neuroglial heterotopia is exceptionally rare, with isolated cases published in the scientific literature.
UNASSIGNED: Here, we present the case of a 3-year-old girl who was admitted without clinical signs but presented with a palpable abdominal mass. Ultrasonography and computed tomography scans revealed a sizable cystic lesion within the retroperitoneal space. Subsequently, laparoscopic resection was performed. Histological examination unveiled neuroglial cell-lined cysts encompassing fibrous connective tissue, ganglia, glial tissue, and nerve bundles. Notably, distinct areas and cell types exhibited expression of S100, glial fibrillary acidic protein, and neuron-specific enolase. Follow-up assessments revealed no relapses or late complications.
UNASSIGNED: In cases of retroperitoneal neuroglial heterotopia, most children may remain asymptomatic without any congenital anomalies. Despite their detectability through imaging, accurate preoperative diagnosis is seldom achieved. Generally, a favorable prognosis follows complete surgical resection, although further cases are required to confirm its long-term efficacy, necessitating extended follow-up for verification.
UNASSIGNED: Here, we present the case of a 3-year-old girl who was admitted without clinical signs but presented with a palpable abdominal mass. Ultrasonography and computed tomography scans revealed a sizable cystic lesion within the retroperitoneal space. Subsequently, laparoscopic resection was performed. Histological examination unveiled neuroglial cell-lined cysts encompassing fibrous connective tissue, ganglia, glial tissue, and nerve bundles. Notably, distinct areas and cell types exhibited expression of S100, glial fibrillary acidic protein, and neuron-specific enolase. Follow-up assessments revealed no relapses or late complications.
UNASSIGNED: In cases of retroperitoneal neuroglial heterotopia, most children may remain asymptomatic without any congenital anomalies. Despite their detectability through imaging, accurate preoperative diagnosis is seldom achieved. Generally, a favorable prognosis follows complete surgical resection, although further cases are required to confirm its long-term efficacy, necessitating extended follow-up for verification.
摘要：
■神经胶质异位症是一种罕见的病变，由分化的神经外胚层细胞组成，表现在颅外位置，大多数病例主要发生在头颈部。腹膜后神经胶质异位症非常罕见，科学文献中发表的孤立病例。
■这里，我们介绍了一例3岁女孩的病例,她入院时没有临床症状,但表现为可触及的腹部肿块.超声检查和计算机断层扫描显示腹膜后间隙内有相当大的囊性病变。随后，进行腹腔镜切除。组织学检查揭示了神经胶质细胞衬里的囊肿，包括纤维结缔组织，神经节,胶质组织，和神经束。值得注意的是,不同区域和细胞类型表现出S100，胶质纤维酸性蛋白的表达，和神经元特异性烯醇化酶。随访评估显示无复发或晚期并发症。
■在腹膜后神经胶质异位症的病例中，大多数儿童可能保持无症状，没有任何先天性异常。尽管它们可以通过成像检测，准确的术前诊断很少实现。一般来说,完全手术切除后预后良好，尽管需要更多的病例来确认其长期疗效，需要延长核查的后续行动。
■这里，我们介绍了一例3岁女孩的病例,她入院时没有临床症状,但表现为可触及的腹部肿块.超声检查和计算机断层扫描显示腹膜后间隙内有相当大的囊性病变。随后，进行腹腔镜切除。组织学检查揭示了神经胶质细胞衬里的囊肿，包括纤维结缔组织，神经节,胶质组织，和神经束。值得注意的是,不同区域和细胞类型表现出S100，胶质纤维酸性蛋白的表达，和神经元特异性烯醇化酶。随访评估显示无复发或晚期并发症。
■在腹膜后神经胶质异位症的病例中，大多数儿童可能保持无症状，没有任何先天性异常。尽管它们可以通过成像检测，准确的术前诊断很少实现。一般来说,完全手术切除后预后良好，尽管需要更多的病例来确认其长期疗效，需要延长核查的后续行动。
