关键词: Biorefinery Cellulase Cellulose Mechanism Techno-economic aspects

来  源:   DOI:10.1186/s40643-021-00447-6   PDF(Pubmed)

Abstract:
The potential of cellulolytic enzymes has been widely studied and explored for bioconversion processes and plays a key role in various industrial applications. Cellulase, a key enzyme for cellulose-rich waste feedstock-based biorefinery, has increasing demand in various industries, e.g., paper and pulp, juice clarification, etc. Also, there has been constant progress in developing new strategies to enhance its production, such as the application of waste feedstock as the substrate for the production of individual or enzyme cocktails, process parameters control, and genetic manipulations for enzyme production with enhanced yield, efficiency, and specificity. Further, an insight into immobilization techniques has also been presented for improved reusability of cellulase, a critical factor that controls the cost of the enzyme at an industrial scale. In addition, the review also gives an insight into the status of the significant application of cellulase in the industrial sector, with its techno-economic analysis for future applications. The present review gives a complete overview of current perspectives on the production of microbial cellulases as a promising tool to develop a sustainable and greener concept for industrial applications.
摘要:
纤维素分解酶的潜力已被广泛研究和探索用于生物转化过程,并在各种工业应用中起着关键作用。纤维素酶,富含纤维素的废物原料为基础的生物炼制的关键酶,各个行业的需求不断增加,例如,纸张和纸浆,果汁澄清,等。此外,在制定提高产量的新战略方面不断取得进展,例如将废物原料用作生产单独或酶混合物的底物,工艺参数控制,和遗传操作以提高产量生产酶,效率,和特异性。Further,还提出了对固定化技术的见解,以提高纤维素酶的可重用性,在工业规模上控制酶成本的关键因素。此外,该评论还深入了解了纤维素酶在工业部门的重要应用现状,及其未来应用的技术经济分析。本综述全面概述了微生物纤维素酶生产的当前观点,将其作为开发工业应用的可持续和绿色概念的有前途的工具。
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