Abstract：
We report a long-term remission in candidiasis in a 57-year-old Finnish female with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) suffering from recurrent oral, esophageal, gastric, vaginal, and anal candidiasis since childhood. Candidiasis treatment with antifungal medicines fluconazole, itraconazole, posaconazole, voriconazole, caspofungin, nystatin, or amphotericin-B during 2008-2021 had variable effects and intermittent development of antifungal resistance and hospital periods. The patient started using fermented lingonberry juice (FLJ) as a mouth rinse daily in April 2021. No symptoms or mucosal signs of candidiasis in any part of the digestive system or vaginal area have been noticed during this exceptionally long-term 2 ½ year remission in candidiasis without antifungal medications.
摘要：
我们报告了一名57岁的芬兰女性念珠菌病的长期缓解，该女性患有自身免疫性多内分泌病-念珠菌病-外胚层营养不良（APECED），患有复发性口腔，食道,胃,阴道,和肛门念珠菌病从小。用抗真菌药物氟康唑治疗念珠菌病，伊曲康唑,泊沙康唑,伏立康唑,卡波芬金,在2008-2021年期间，制霉菌素或两性霉素B具有不同的作用，并且出现了抗真菌耐药性和住院期间的间歇性发展。该患者于2021年4月开始每天使用发酵越橘汁（FLJ）作为漱口水。在没有抗真菌药物的情况下，在念珠菌病的这种异常长期的2½年缓解期间，在消化系统或阴道区域的任何部位均未发现念珠菌病的症状或粘膜体征。
