Abstract：
UNASSIGNED: Benign prostatic hyperplasia (BPH) affects 30% of men worldwide, folate is essential for life. However, few studies have investigated the relationship between folate levels and BPH. The present study aims to explore the relationship between red blood cell (RBC) folate, a better indicator of long-term folate intake, and BPH in United States (US) men.
UNASSIGNED: We used statistics from four cycles of the \"National Health and Nutrition Examination Survey\" (NHANES2001-2008), RBC folate data come from laboratory data and BPH date come from questionnaire data. A multivariate conditional logistic regression model and subgroup analysis were using to assess the association between RBC folate and BPH.
UNASSIGNED: 647 males from four survey cycles in the NHANES2001-2008, of which, 574 men (88.7%) had BPH. After adjusting for potential confounders, a considerable correlation was observed between RBC folate and BPH; With the first quintiles of RBC folate as the reference, multivariable-adjusted odds ratios (ORs) and confidence intervals (95% CIs) of the second, third, fourth, and the highest quintiles were 1.19 (0.58 ∼ 2.44), 1.39 (0.65 ∼ 2.97), 2.27 (0.96 ∼ 5.39), 2.26 (1.35 ∼ 3.76) and 5.37 (1.85 ∼ 15.59), respectively.
UNASSIGNED: Individuals with high levels of RBC folate were associated with an increased risk of self-reported benign prostatic hyperplasia of US men.
UNASSIGNED: We used statistics from four cycles of the \"National Health and Nutrition Examination Survey\" (NHANES2001-2008), RBC folate data come from laboratory data and BPH date come from questionnaire data. A multivariate conditional logistic regression model and subgroup analysis were using to assess the association between RBC folate and BPH.
UNASSIGNED: 647 males from four survey cycles in the NHANES2001-2008, of which, 574 men (88.7%) had BPH. After adjusting for potential confounders, a considerable correlation was observed between RBC folate and BPH; With the first quintiles of RBC folate as the reference, multivariable-adjusted odds ratios (ORs) and confidence intervals (95% CIs) of the second, third, fourth, and the highest quintiles were 1.19 (0.58 ∼ 2.44), 1.39 (0.65 ∼ 2.97), 2.27 (0.96 ∼ 5.39), 2.26 (1.35 ∼ 3.76) and 5.37 (1.85 ∼ 15.59), respectively.
UNASSIGNED: Individuals with high levels of RBC folate were associated with an increased risk of self-reported benign prostatic hyperplasia of US men.
摘要：
■良性前列腺增生（BPH）影响全球30％的男性，叶酸是生命所必需的。然而,很少有研究调查叶酸水平与BPH之间的关系。本研究旨在探讨红细胞(RBC)叶酸、长期叶酸摄入量的更好指标，和BPH在美国（美国）男性。
■我们使用了“国家健康和营养调查”（NHANES2001-2008）的四个周期的统计数据，RBC叶酸数据来自实验室数据，BPH数据来自问卷数据。使用多因素条件逻辑回归模型和亚组分析来评估红细胞叶酸和BPH之间的关联。
■在NHANES2001-2008年的四个调查周期中，647名男性，574名男性（88.7%）患有BPH。在调整了潜在的混杂因素后，在红细胞叶酸和BPH之间观察到相当大的相关性；以红细胞叶酸的前五分之一为参考，秒的多变量调整后的优势比(OR)和置信区间(95%CI)，第三,第四,最高的五分位数为1.19(0.58~2.44)，1.39(0.65~2.97)，2.27(0.96~5.39)，2.26(1.35~3.76)和5.37(1.85~15.59)，分别。
■红细胞叶酸水平高的个体与美国男性自我报告的良性前列腺增生的风险增加相关。
■我们使用了“国家健康和营养调查”（NHANES2001-2008）的四个周期的统计数据，RBC叶酸数据来自实验室数据，BPH数据来自问卷数据。使用多因素条件逻辑回归模型和亚组分析来评估红细胞叶酸和BPH之间的关联。
■在NHANES2001-2008年的四个调查周期中，647名男性，574名男性（88.7%）患有BPH。在调整了潜在的混杂因素后，在红细胞叶酸和BPH之间观察到相当大的相关性；以红细胞叶酸的前五分之一为参考，秒的多变量调整后的优势比(OR)和置信区间(95%CI)，第三,第四,最高的五分位数为1.19(0.58~2.44)，1.39(0.65~2.97)，2.27(0.96~5.39)，2.26(1.35~3.76)和5.37(1.85~15.59)，分别。
■红细胞叶酸水平高的个体与美国男性自我报告的良性前列腺增生的风险增加相关。
