Abstract：
Delayed union of fractures is one of the most frequent complications in orthopedic practice, especially in polytrauma patients. With the development of new methods of regenerative medicine, including the use of adipose derived stromal cells as a component of the stromal-vascular fraction (SVF), new possibilities for conservative treatment of this problem have emerged. This article presents a clinical case of conservative treatment of delayed union of a radial bone fracture using local SVF injections. In the fracture space, SVF with PRP creates a pool of cells that could differentiate towards surrounding tissue, releases various inducers of tissue growth and, via an indirect chemotactic effect on receptors, mobilizes the body\'s own resources and creates conditions for angiogenesis and trophism in the injured segment. In the patient with delayed consolidation after SFV-therapy, progress in clinical and radiological dynamics was noted with complete healing within 7 months. The positive clinical result provides a basis for further study and implementation in practice.
摘要：
骨折延迟愈合是骨科实践中最常见的并发症之一，尤其是多发伤患者。随着再生医学新方法的发展,包括使用脂肪来源的基质细胞作为基质血管部分（SVF）的组成部分，保守治疗这个问题的新可能性已经出现。本文介绍了使用局部SVF注射保守治疗桡骨骨折延迟愈合的临床病例。在断裂空间，带有PRP的SVF产生了一个可以向周围组织分化的细胞池，释放各种组织生长诱导剂，通过对受体的间接趋化作用，动员身体自身的资源，为受伤部位的血管生成和营养创造条件。在SFV治疗后延迟巩固的患者中，观察到临床和放射学动力学进展,并在7个月内完全愈合.积极的临床结果为进一步研究和在实践中实施提供了依据。
