PDF(Pubmed)
Abstract：
This study aimed to assess the efficacy of human amniotic membranes (HAM) in treating venous and diabetic ulcers, which often pose challenges in healing. A systematic review and meta-analysis were conducted, evaluating 10 relevant studies involving 633 participants. Findings revealed that HAM treatment significantly accelerated ulcer closure, demonstrating over 90% complete healing compared to standard care. Despite moderate heterogeneity among studies, the results strongly suggested the effectiveness and safety of HAM therapy for venous and diabetic leg ulcers. Further research with larger study cohorts is recommended to bolster the existing evidence supporting HAM in managing these challenging wounds.
摘要：
本研究旨在评估人羊膜（HAM）治疗静脉和糖尿病性溃疡的疗效。这通常会给治疗带来挑战。进行了系统评价和荟萃分析，评估10项相关研究，涉及633名参与者。研究结果表明，HAM治疗显着加速溃疡闭合，与标准护理相比，显示90%以上的完全愈合。尽管研究之间存在中等异质性，结果强烈提示HAM治疗静脉性和糖尿病性腿部溃疡的有效性和安全性.建议对更大的研究队列进行进一步的研究，以支持支持HAM管理这些挑战性伤口的现有证据。
